Population-based stroke and dementia incidence trends: Age and sex variations |
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| Authors: | Joshua O Cerasuolo Lauren E Cipriano Luciano A Sposato Moira K Kapral Jiming Fang Sudeep S Gill Daniel G Hackam Vladimir Hachinski |
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| Institution: | 1. Department of Epidemiology and Biostatistics, Schulich School of Medicine & Dentistry, Western University, London, Ontario, Canada;2. Ivey Business School, Western University, London, Ontario, Canada;3. Department of Clinical Neurological Sciences, London Health Sciences Centre, Western University, London, Ontario, Canada;4. Department of Medicine, University of Toronto, Toronto, Ontario, Canada;5. Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada;6. Institute for Clinical Evaluative Sciences, Queen''s University, Kingston, Ontario, Canada;7. Division of Geriatric Medicine, Queen''s University, Kingston, Ontario, Canada;8. Division of Geriatric Medicine, St. Mary''s of the Lake Hospital, Kingston, Ontario, Canada;9. Division of Clinical Pharmacology, Department of Medicine, Western University, London, Ontario, Canada |
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| Abstract: | IntroductionWe discovered a concomitant decline in stroke and dementia incidence rates at a whole population level in Ontario, Canada. This study explores these trends within demographic subgroups.MethodsWe analyzed administrative data sources using validated algorithms to calculate stroke and dementia incidence rates from 2002 to 2013.ResultsFor more than 12 years, stroke incidence remained unchanged among those aged 20 to 49 years and decreased for those aged 50 to 64, 65 to 79, and 80+ years by 22.7%, 36.9%, and 37.9%, respectively. Dementia incidence increased by 17.3% and 23.5% in those aged 20 to 49 and 50 to 64 years, respectively, remained unchanged in those aged 65 to 79 years, and decreased by 15.4% in those aged 80+ years.DiscussionThe concomitant decline in stroke and dementia incidence rates may depict how successful stroke prevention has targeted shared risk factors of both conditions, especially at advanced ages where such risk factors are highly prevalent. We lend support for the development of an integrated system of stroke and dementia prevention. |
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| Keywords: | Age Dementia Incidence Sex Stroke Temporal Trend Epidemiology |
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