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雌激素膜受体GPR30在成年雄性大鼠脊髓中的表达
引用本文:孙浩东,胡荣,冯华,林江凯,夏永志,赵天智,罗海水,李兰.雌激素膜受体GPR30在成年雄性大鼠脊髓中的表达[J].中国临床神经外科杂志,2010,15(4):228-230.
作者姓名:孙浩东  胡荣  冯华  林江凯  夏永志  赵天智  罗海水  李兰
作者单位:第三军医大学西南医院神经外科,重庆,400038
摘    要:目的研究雌激素膜受体—G蛋白偶联受体30(GPR30)在正常成年大鼠脊髓中的表达与分布。方法采用免疫组化染色法观察4只成年大鼠脊髓各节段中GPR30的表达和分布情况。结果在脊髓的各个节段,GPR30在脊髓中均有表达,但主要分布在灰质中,且以腹角为主,除腰段脊髓背角有少量GPR30阳性信号外,其余节段脊髓背角均未见明显GPR30阳性信号。GPR30在白质中的信号分布较均匀。结论GPR30在脊髓呈特异性分布,提示其在脊髓的生理和病理过程中可能起重要的作用。

关 键 词:大鼠  脊髓  雌激素  膜受体  GPR30

Expression of estrogen membrane receptor,G protein-coupled receptor 30 in the spinal cords of adult rats
SUN Hao-dong,HU Rong,FENG Hua,LIU Jiang-kai,XIA Yong-zhi,ZHAO Tian-zhi,LUO Hai-shui,LI Lan.Expression of estrogen membrane receptor,G protein-coupled receptor 30 in the spinal cords of adult rats[J].Chinese Journal of Clinical Neurosurgery,2010,15(4):228-230.
Authors:SUN Hao-dong  HU Rong  FENG Hua  LIU Jiang-kai  XIA Yong-zhi  ZHAO Tian-zhi  LUO Hai-shui  LI Lan
Institution:SUN Hao-dong,HU Rong,FENG Hua,LIU Jiang-kai,XIA Yong-zhi,ZHAO Tian-zhi,LUO Hai-shui,LI Lan.Department of Neurosurgery,Southwest Hospital,Third Military Medical University,Chongqing 400038,China
Abstract:Objective To investigate the expression and distribution of estrogen membrane receptor,G protein-coupled receptor 30( GPR30)in the spinal cords of the adult rats.Methods The expression and distribution of GPR30 in the spinal cords of 4 male adult ratsw ere determined by immunohistochemistry.Results GPR30-positive signal was detected in both the gray and white matter of 4 male rats pinal cord,in which GPR30 was mainly distributed in the gray matter,especially in its ventral horn.No significantly GPR30-positi...
Keywords:GPR30
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