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重型颅脑损伤患者脑灌注压与颈内静脉血氧饱和度的关系
引用本文:徐福林,王建清,李宁,全勇,贾丕丰,盖延廷,茅宇航,沈刚,沈建康.重型颅脑损伤患者脑灌注压与颈内静脉血氧饱和度的关系[J].中国临床神经外科杂志,2011,16(2):72-74.
作者姓名:徐福林  王建清  李宁  全勇  贾丕丰  盖延廷  茅宇航  沈刚  沈建康
作者单位:1. 上海市闵行区中心医院神经外科,201100
2. 上海市瑞金医院神经外科,200025
摘    要:目的评估颈内静脉血氧饱和度(SjvO2)作为重型颅脑损伤的预后指标可能性及其与脑灌注压(CPP)的相关性。方法重型颅脑损伤病人52例,每6h测定一次SjvO2,持续监测平均动脉压及颅内压,计算出CPP,分析SjvO2与预后的相关性。结果在监测期间有2次或2次以上SjvO2<50%或SjvO2>75%者预后良好率明显低于SjvO250%~75%者或仅有一次SjvO2<50%或SjvO2>75%者(P<0.01)。CPP≤60mmHg者,SjvO2与CPP显著正相关(r=0.679,P<0.01),而CPP>60mmHg者,SjvO2与CPP无明显相关(P>0.05)。结论 SjvO2和CPP联合监测能较可靠地预测重型颅脑损伤患者的预后。

关 键 词:重型颅脑损伤  脑灌注压  颈内静脉血氧饱和度  预后

Relationship between cerebral perfusion pressure and jugular vein blood oxygen saturation in the patients with severe traumatic brain injury
XU Fu-lin,WANG Jian-qing,LI Ning,QUAN Yong,JIA Pei-feng,GAI Yan-ting,MAO Yu-hang,SHEN Gang,SHEN Jian-kang.Relationship between cerebral perfusion pressure and jugular vein blood oxygen saturation in the patients with severe traumatic brain injury[J].Chinese Journal of Clinical Neurosurgery,2011,16(2):72-74.
Authors:XU Fu-lin  WANG Jian-qing  LI Ning  QUAN Yong  JIA Pei-feng  GAI Yan-ting  MAO Yu-hang  SHEN Gang  SHEN Jian-kang
Institution:. (Department of Neurosurgery, Minghang District Central Hospital, Shanghai 201100, China)
Abstract:Objective To explore the possibility of jugular vein blood oxygen saturation (SjvO2) serving as indicators of prognosis and its relationship with the cerebral perfusive pressure (CPP) in the patients with severe traumatic brain injury (sTBI). Methods The SjvO2 was determined every 6 hours, the mean arterial pressure (MAP) and intracranial pressure(ICP) were continuously monitored in 52 patients with sTBI. CPP was calculated. The relationship of SjvO2 and CPP with the prognosis was analyzed in all the patients. Results The rate of the good prognosis in the patients who had 2 or more than 2 times SjvO2〈50% or 〉75% was significantly lower than that in the patients who had 50%-75% SjvO2 or only 1 time SjvO2〈50% or 〉75% during monitoring SilO2 (P〈0.01). The CPP was positively related to SjvO2 in the patients with CPP〈60 mmHg (P〈0.01) and not to the SjvO2 in the patients with CPP≥60 mmHg (P〉0.05). Conclusion SjvO2 combined with CPP may be reliable to predict prognosis in the patients with sTBI.
Keywords:Severe traumatic brain injury  Jugular vein  Blood oxygen saturation  Cerebral perfusion pressure  Prognosis
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