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中国人脊髓亚急性联合变性的临床特点(附40例分析)
引用本文:樊春秋,贾建平.中国人脊髓亚急性联合变性的临床特点(附40例分析)[J].中国神经精神疾病杂志,2005,31(2):108-110.
作者姓名:樊春秋  贾建平
作者单位:首都医科大学宣武医院神经内科,北京,100053
摘    要:目的 探讨脊髓亚急性联合变性(SCD)在中国发病的临床特点。方法 总结本组4 0例患者的临床资料;与同期国内外相关资料进行对比。结果 93 .3% ( 2 8/30 )患者现肌电图异常改变;脊髓MR检查发现1 2 /2 5患者脊髓后索存在特异性异常改变;35 .0 % ( 1 4 /40 )患者伴有贫血;1 3/2 3患者血清VitB12 水平降低;应用VitB12 治疗所有患者均有不同程度的好转。结论 我国SCD有其自身发病特点;试验性VitB12 治疗有效对明确诊断有重要意义;脊髓MR扫描可以辅助诊断。

关 键 词:脊髓亚急性联合变性  诊断  维生素B_(12)
修稿时间:2004年8月25日

A clinical characteristics of subacute combined degeneration of spinal cord in Chinese
Fan Chun-qiu,JIA Jian-ping.A clinical characteristics of subacute combined degeneration of spinal cord in Chinese[J].Chinese Journal of Nervous and Mental Diseases,2005,31(2):108-110.
Authors:Fan Chun-qiu  JIA Jian-ping
Institution:FAN Chun-qiu,JIA Jian-ping. Department of Neurology,Xuanwu Hospital,45 changchun street,Beijing. 100053.
Abstract:Objective To analyze the clinical characteristics of Chinese patients with subacute combined degeneration of the spinal cord(SCD). Methods The detail clinical materials of forty patients with SCD were investigated. Results Twenty-eight of thirty patients(93.3%) showed abnormal changes in electromyography. Among twenty-five patients, MR image exhibited special abnormal signal intensity in the dorsal columns of spinal cord in twelve patients(48.0%). Anemia was found in 14 of 40 cases (35.0%). The serum VitB 12 level was low in 13 of 23 cases(56.5%). All patients got effectiveness after treatment with VitB 12 . Conclusions Chinese patients with SCD have some clinical characteristics different from other population. Chinical improvement after VitB 12 treatment plays an important role in diagnosis of SCD; MR image of spinal cord is also useful for the diagnosis.
Keywords:Subacute combined degeneration  Diagnosis  Vitamin B_(12)
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