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急性缺血性脑卒中患者出血转化与血脂水平的关系
引用本文:汤媛媛,秦超,梁志坚,赵伟佳,李茂,龙莉玲.急性缺血性脑卒中患者出血转化与血脂水平的关系[J].中国神经精神疾病杂志,2011,37(12).
作者姓名:汤媛媛  秦超  梁志坚  赵伟佳  李茂  龙莉玲
作者单位:1. 广西医科大学第一附属医院神经内科,南宁,530021
2. 广西医科大学第一附属医院放射科
摘    要:目的 探讨血脂水平对急性缺血性脑卒中出血转化(hemorrhagic transformation,HT)影响及其规律.方法 连续收录广西医科大学第一附院神经内科2009年1月至2010年12月期间确诊急性缺血性脑卒中病例.收录内容包括性别、起病年龄、既往病史、神经功能缺失严重程度、血压、血糖、血脂水平、缺血性脑卒中病因、梗死面积及部位.以上因素与HT关系采用非条件Logistic回归分析.结果 共纳入665例急性缺血性脑卒中病例,HT68例.大面积梗死、皮层梗死、空腹血糖、空腹血清总胆同醇水平、既往高血压史与HT有关:空腹血清总胆固醇水平每降低l mmol/L,HT发生率增高35.6%(OR:0.644;95%CI:0.456~0.908;P=0.012).结论 空腹血清总胆固醇水平与HT有关;随着空腹血清总胆同醇水平降低,HT发生率呈增高趋势.

关 键 词:急性缺血性脑卒中继发出血转化  血清总胆固醇

Study on the relationship of hemorrhagic transformation after acute ischemic stroke and the level of fasting blood lipid
TANG Yuanyuan,QIN Chao,LIANG Zhijian,ZHAO Weijia,LI Mao,LONG Liling.Study on the relationship of hemorrhagic transformation after acute ischemic stroke and the level of fasting blood lipid[J].Chinese Journal of Nervous and Mental Diseases,2011,37(12).
Authors:TANG Yuanyuan  QIN Chao  LIANG Zhijian  ZHAO Weijia  LI Mao  LONG Liling
Institution:TANG Yuanyuan,QIN Chao,LIANG Zhijian,ZHAO Weijia,LI Mao,LONG Liling.Department of Neurology,the First Affiliated HospitalGuangxi Medical University,Guangxi Nanning 530021,China
Abstract:Objiective To discuss the relationship of hemorrhagic transformation(HT) after acute ischemic stroke and the level of fasting blood lipid.Methods Consecutive patients admitted to the First Affiliated Hospital to Guangxi Medical University with objectively diagnosed acute ischemic stroke between 1 January 2009 and 31 December 2010 were included.At admission,baseline demographic and clinical information was collected including gender,age of onset,past medical history,systolic blood pressure and diastolic bloo...
Keywords:Hemorrhagic Transformation After Acute Ischemic Stroke Total Cholesterol Low-Density Lipoprotein Cholesterol Logistic regression analysis  
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