首页 | 本学科首页   官方微博 | 高级检索  
检索        

中青年脑梗塞患者的临床与病理
引用本文:王德生,徐心.中青年脑梗塞患者的临床与病理[J].中华神经科杂志,1998,31(2):98-101.
作者姓名:王德生  徐心
作者单位:哈尔滨医科大学第一临床医学院神经内科,哈尔滨医科大学病理教研室
摘    要:目的 探讨中,青年人脑梗塞的病因。方法 将连续尸检确诊的脑梗塞病例中≤45岁患者的脑标本常规处理,以动脉为重点行肉眼及光镜下观察,并分析有关临床资料。结果 72例患者中≤45岁者7例,其中男6例,女1例,其中高血压,风湿性心脏病各2例,嗜烟,嗜酒中4例,病前1日酗酒1例。便塞灶相关动脉闭塞处管壁5例发现粥样斑块,3例发现炎症(1例与粥样斑并存)。5例粥样斑块血栓形成均位于基底动脉,4例病后2日内死

关 键 词:脑梗塞  病理学  临床  中青年人

Cerebral infarction in the middle aged and young adults: clinical and pathological study
Abstract:Objective To assess the pathogenic factors of cerebral infarction in the middle aged and young adults. Method Microscopic examination of the conventionally prepared autopsy brain specimens was made with particular attention to the arterial walls and lumens, and the relevant clinical materials were analysed. Results Among the 72 consecutive autopsy confirmed cases of cerebral infarction, seven cases (9.72%, six males and one female) were at or below the age of 45 years and were included in this study. In the seven cases there were two with hypertension, two with rheumatic heart disease, four smokers, four drinkers (one of them had an excessive drinking on the day before the onset of infarction), and one with the history of an ischemic stroke. The walls of the infarct related arterial segments were identified. The atheromatous plaque based thrombosis was observed in five cases. They all occurred in the basilar arteries, causing deaths within two days after the onset of the strokes in four cases. There were inflammatory changes in three cases, in one of which there were both inflammation and an atheromatous plaque. In the two cases without apparent atherosclerosis, there was occlusion of the left middle cerebral artery, which resulted in deaths 7 and 30 days after the onset of the strokes respectively. Four cases developed cerebral hernia. No other evident complication was found in any of the seven cases. Conclusions In the cases of cerebral infarction found among the middle aged and young adults, atherosclerosis appeared to be an important pathogenic cause. Heavy cigarette smoking and excessive drinking might be the relevant risk factors. The site of arterial occlusion in relation to the extent or severity of ischemic involvement might be the major factor influencing the survival duration after the first onset of brain infarction. The basic cause of the deaths seemed to be mainly due to the cerebral strokes rather than its complications.
Keywords:Cerebral infarction    Pathology  clinical    The middle  aged and young  
本文献已被 CNKI 维普 等数据库收录!
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号