| 抗心磷脂抗体与脑血管病相关性研究 |
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| 引用本文： | 刘昌勤,夏芸,孙圣刚. 抗心磷脂抗体与脑血管病相关性研究[J]. 卒中与神经疾病, 2000, 7(2): 104-106 |
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| 作者姓名： | 刘昌勤 夏芸 孙圣刚 |
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| 作者单位： | 刘昌勤（430022 同济医科大学附属协和医院神经内科[） 夏芸（430022 同济医科大学附属协和医院神经内科[） 孙圣刚（430022 同济医科大学附属协和医院神经内科[） 童萼塘（430022 同济医科大学附属协和医院神经内科[） |
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| 摘 要： | 目的研究抗心磷脂抗体(ACA)与脑血管病的关系，为脑卒中的预测提供临床依据。方法采用前瞻性研究方法，对91例脑梗死(CI)、42例脑出血(CH)患者及30例健康者血清中的抗心磷脂抗体(ACA)进行检测。结果CI及CH组ACA总阳性率、IgG型ACA阳性率均显著高于对照组。ACA阳性卒中容易复发，病灶常为多个。ACA在脑卒中发病一周内阳性率最高，且抗体分型以IgG型为主。结论ACA是CI及CH的危险因素，对脑卒中的预测有一定意义。
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| 关 键 词： | 抗心磷脂抗体 脑梗死 脑出血 |
| 修稿时间： | 1999-11-15 |
The study of relationship between anticardiolipin antibodyand cerebrovascular diseases |
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| Liu Changqin,Xia Yun,Sun Shenggang. The study of relationship between anticardiolipin antibodyand cerebrovascular diseases[J]. Stroke and Nervous Diseases, 2000, 7(2): 104-106 |
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| Authors: | Liu Changqin Xia Yun Sun Shenggang |
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| Affiliation: | Liu Changqin,Xia Yun,Sun Shenggang(Department of Neurology, Union Hospital, Tongji Medical University,Wuhan 430022) |
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| Abstract: | Objective:To Study the relationship between cerebral vescular diseases and anticardiolipin antibody for providiy a clinical evidence for stroke prediction Methods:Serum ACA was measured in 91 patients with cerebral infarction(CI),42 patients with cerebral hemorrhage(CH)and 30 control subjects.Results:The prenalence of ACA in CI and CH patients was different significantly compared with control and IgG ACA was a most important isotype.Stroke in ACA positive group tended to be recurrent and multiple event.Positive rate of IgG ACA reached its climax within the first week after stroke onset.Conclusion:The results suggested ACA be an independent risk factor in CI and CH and ACA was valuable in stroke prediction. |
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| Keywords: | Anticardiolipin antibody Cerebral infarction Cerebral hemorrhage |
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