| 18F-FDG PET/CT在颞叶内侧癫痫外科定位诊断中的价值 |
| |
| 引用本文： | 蒋伟,马杰,陈旭,吴俊,舒凯,雷霆,李龄.18F-FDG PET/CT在颞叶内侧癫痫外科定位诊断中的价值[J].立体定向和功能性神经外科杂志,2011(5):277-280. |
| |
| 作者姓名： | 蒋伟 马杰 陈旭 吴俊 舒凯 雷霆 李龄 |
| |
| 作者单位： | 华中科技大学同济医学院附属同济医院神经外科; |
| |
| 基金项目： | 湖北省自然科学基金面上项目(编号:2009CDB291); 中国博士后科学基金面上项目(编号:20090460948) |
| |
| 摘 要： | 目的探讨18F-脱氧葡萄糖(FDG)PET/CT检查在颞叶内侧癫痫(mesial temporal lobe epilepsy)术前评估和致痫灶定位中的应用价值。方法回顾性分析我科实施手术治疗的85例颞叶内侧癫痫患者的临床资料,经三大检查(症状学、MRI、V-EEG)和18F-FDG PET/CT检查证实致痫灶存在且位于颞叶内侧。经上述方法精准定位后,采用扩大额颞手术切口,皮层脑电描记引导下施行标准前颞叶切除术,部分加做海马杏仁核切除术或(和)皮层热灼术,对术前评估方法,18F-FDG PET/CT检查的意义和手术治疗预后进行分析。结果 85例患者术后随访6个月到5年,Engel效果分级:69例(81.2%)I级,9例(10.6%)Ⅱ级,7例(8.2%)Ⅲ级或Ⅳ级。4例出现硬膜外血肿,15例出现短期并发症,所有病人均无永久性并发症。患者术后服用抗癫痫药物较术前减少或停药。结论 18 F-FDGPET/CT检查是目前颞叶内侧癫痫致痫灶定位精确、直观而有效的手段之一,结合常规三大术前检查,是颞叶内侧癫痫致痫灶定位可靠的无创性检查方法。18F-FDG PET/CT检查对于颞叶内侧癫痫的术前定位诊断具有重要价值。
|
| 关 键 词： | 颞叶内侧癫痫 18F-FDGPET/CT检查 致痫灶定位 外科手术治疗 |
~(18)F-FDG PET/CT in the localization of epileptogenic foci of mesial temporal lobe epilepsy surgery |
| |
| Jiang Wei,Ma Jie,Chen Xu,et al..~(18)F-FDG PET/CT in the localization of epileptogenic foci of mesial temporal lobe epilepsy surgery[J].Chinese Journal of Stereotactic and Functional Neurosurgery,2011(5):277-280. |
| |
| Authors: | Jiang Wei Ma Jie Chen Xu |
| |
| Institution: | Jiang Wei,Ma Jie,Chen Xu,et al.Department of Neurosurgery,Tongji Hospital,Huazhong University of Science and Technology,Wuhan,430030,China |
| |
| Abstract: | Objective To evaluate the role of 18F-FDG PET/CT in the localization of epileptogenic foci of mesial temporal lobe epilepsy surgery.Methods Eighty-five patients with mesial temporal lobe epilepsy were included retrospectively.All cases underwent semeiotic analysis,MRI,V-EEG and 18F-FDG PET/CT for pre-surgical evaluation,followed with various surgeries(anterior temporal lobectomy,selective amygdalo-hippocampectomy and/or electro-coagulation on cerebral cortexes) according to the evaluation.Analyze the pre-su... |
| |
| Keywords: | Mesial temporal lobe epilepsy 18F-FDG PET/CT Localization of epileptogenic foci Surgery |
| 本文献已被 CNKI 等数据库收录！ |
|
