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Tick-borne Encephalitis: Stroke-like Presentation
Authors:Andreas Eleftheriou  Fredrik Lundin  Evangelos Alexandros Petropoulos
Institution:2. Department of Clinical Microbiology, Karolinska University Hospital, Stockholm, Sweden;3. Department of Neurology, University Hospital, Linköping, Sweden
Abstract:Tick-borne encephalitis, caused by the tick-borne virus (TBEV), is endemic in central, eastern, and northern Europe eastwards through Russian Siberia and China. For the year 2009, the highest incidence in Scandinavian countries was in Sweden. The clinical symptoms have a wide spectrum. We report a unique case of clinical symptoms and radiological findings compatible with a stroke-like inflammatory lesion in the thalamus, suggesting microangiopathy from TBEV. Our case shows that TBEV could be a possible cause of stroke-like lesions.
Keywords:Address correspondence to Andreas Eleftheriou  MD  Department of Neurology  University Hospital  Garnisonsvägen 10  58750 Linköping  Sweden    Tick-borne encephalitis  thalamus  cerebral infarction  cerebrovascular disease  DWI  ADC  TBE  tick-borne encephalitis  TBEV  tick-borne virus  CNS  central nervous system  BPM  beats per minute  CRP  c - reactive protein  CT  computer tomography  LP  lumbar puncture  ER  emergency department  CSF  cerebrospinal fluid  MRI  magnet resonance imaging  TOF  time of flight angiography  VIEU  VIENNA units  FLAIR  T2-weighted-fluid-attented inversion recovery  DWI  diffusion-weighted magnetic-resonance imaging  ADC  apparent diffusion coefficient  TLR3  toll-like receptor 3  dsRNA  double-stranded ribonucleic acid  NK  natural killers  CCR5  C-C chemokine receptor type 5  IgG  immunoglobulin
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