耳鸣评价量表（TEQ）的耳鸣疗效评定新标准探索

目的通过对比耳鸣评价量表(TEQ)治疗前后得分变化和等级变化计算的疗效,并与耳鸣残疾评估量表(THI)的疗效相对比,为TEQ评估耳鸣疗效的评定标准提供参考。方法 TEQ得分疗效是根据国际上使用的标准差/2原则,即治疗前后得分变化≥TEQ初诊得分标准差/2视为治疗有效;TEQ等级疗效是TEQ等级变化≥1级视为治疗有效。THI得分疗效标准分为文献推荐的变化≥7分和变化≥20分,及标准差/2计算的变化≥12分分别视为有效。结果本次调查的165例患者中,按TEQ得分原则(SD/2原则)、TEQ等级原则、THI7分原则、THI12分原则(SD/2原则)及THI20分原则计算的疗效分别为60.00%、49.09%、61.82%、52.73%、及32.73%。通过卡方检验,TEQ得分疗效及TEQ等级疗效与THI7分及THI12分疗效比较均无统计学差异(P>0.005),均明显高于THI20分疗效(P<0.005)。结论使用耳鸣评价量表(TEQ)进行耳鸣疗效评定时,除了通过等级变化外,还可以采用以治疗前后得分变化为基础的疗效评定标准。

A New Standard for Evaluating Efficacy of Tinnitus Evaluation Scale(TEQ) in Assessing Treatment-Related Tinnitus Changes

Objective To investigate the efficacy of the Tinnitus Effets Questionnaire(TEQ) in assessing tinnitus changes after treatment, in comparison with the Tinnitus Handicap Inventory(THI). Methods The TEQ and THI were administered before and after treatment to determine treatment outcomes in 165 patients with tinnitus. In accordance with internationally accepted standards, treatment was considered as effective when the pre-/post-treatment TEQ score differential was equal to or greater than standard deviation of the mean pre-treatment score divided by 2(SD/2) or post-treatment TEQ grade change ≥ 1. By THI, treatment was considered effective if THI score change was ≥ 7, 20 or12(SD/2), as recommended by the literature. Results According to the criteria described above, treatment was effective in 60.00%, 49.09%, 61.82%, 52.73% and 32.73% of the 165 patients by TEQ score change ≥ SD/2, TEQ grade change ≥ 1, THI score change ≥ 7, 12(SD/2) or 20, respectively, with no statistically significant difference among the first four(P>0.05), although they were all higher than that based on THI score change ≥ 20(P<0.05). Conclusion When evaluating the efficacy of tinnitus treatment, TEQ score change, in addition to grade changes, can also be used.