Impact of CAD/CAM mandibular reconstruction on chewing and swallowing function after surgery for locally advanced oral cancer: A retrospective study of 50 cases |
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| Authors: | Akira Ohkoshi Naoko Sato Koreyuki Kurosawa Hitoshi Miyashita Ryo Ishii Ayako Nakanome Takenori Ogawa Masahiro Tachi Tetsu Takahashi Yukio Katori |
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| Institution: | 1. Department of Otorhinolaryngology, Head and Neck Surgery, Tohoku University Graduate School of Medicine, 1-1 Seiryo-cho, Aoba-ku, Sendai 980-8575, Japan;2. Maxiilofacial Prosthetics Clinic, Tohoku University Hospital, 1-1 Seiryo-cho, Aoba-ku, Sendai 980-8575, Japan;3. Department of Plastic and Reconstructive Surgery, Tohoku University Graduate School of Medicine, 1-1 Seiryo-cho, Aoba-ku, Sendai 980-8575, Japan;4. Division of Oral and Maxillofacial Surgery, Tohoku University Graduate School of Dentistry, 1-1 Seiryo-cho, Aoba-ku, Sendai 980-8575, Japan;5. Department of Otolaryngology, Gifu University Graduate School of Medicine, 1-1 Yanagido, Gifu City 501-1193, Japan;1. Fudan University, Shanghai, China;2. Department of Otology and Skull Base Surgery, Eye Ear Nose & Throat Hospital, Fudan University, Shanghai 200031, China;3. Shanghai Auditory Medical Center, Shanghai, China;4. Key laboratory of Hearing Science, Ministry of Health, Shanghai, China;5. Department of Economics, London School of Economics and Political Science, London, United Kingdom;6. Department of Power Mechanical Engineering, National Formosa University, Yunlin, Taiwan;7. Numerical and Scientific Computing Laboratory, National Formosa University, Yunlin, Taiwan;1. Department of Otolaryngology - Head and Neck Surgery, Chang Gung Memorial Hospital, Taoyuan, Taiwan;2. Department of Otolaryngology - Head and Neck Surgery, Chang Gung Memorial Hospital, Keelung, Taiwan;3. Department of Otolaryngology—Head and Neck Surgery, Chang Gung Memorial Hospital, Chiayi, Taiwan;4. Division of Pulmonary, Critical Care, and Sleep Medicine, Chang Gung Memorial Hospital, Keelung, Taiwan;5. College of Medicine, Chang Gung University, Taoyuan, Taiwan;1. Department of Otorhinolaryngology, Medistate Kavac?k Hospital, ?stanbul, Turkey;2. Department of Otorhinolaryngology, K?r?kkale Yüksek ?htisas Hospital, 71400 Ba?larba?? Mah. Dr. Ahmet Ay Cad., K?r?kkale, Turkey;3. Faculty of Medicine, Department of Otorhinolaryngology, Hacettepe University, S?hhiye, Ankara Turkey;4. Faculty of Medicine, Department of Radiology, Hacettepe University, 06100 S?hhiye, Ankara Turkey;1. Hadassah Medical School, Hebrew University, Jerusalem, Israel;2. Department of Otolaryngology, Head and Neck Surgery, Kaplan Medical Center, Rehovot, Israel;3. Department of Ophthalmology, Kaplan Medical Center, Rehovot, Israel |
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| Abstract: | ObjectiveComputer-aided design and computer-aided manufacturing (CAD/CAM) techniques are increasingly applied to mandibular reconstruction, but the superiority of this method in oral food intake has not been well established. Considering the extent of mandibular defects, this retrospective study was aimed to clarify the impact of CAD/CAM mandibular reconstruction on chewing and swallowing function after surgery for locally advanced oral cancer.Materials and methodsWe performed a retrospective review of 50 patients who had undergone segmental mandibulectomy with free flap reconstruction for locally advanced oral cancer. The patients’ Functional Oral Intake Scale scores were measured at 3 months after surgery, and possible contributing factors including CAD/CAM mandibular reconstruction and the extent of mandibular defects for oral food intake were subjected to univariate analysis and multivariate logistic regression analysis.ResultsMultivariate logistic regression analysis showed that CAD/CAM mandibular reconstruction was independently associated with good oral intake, whereas both anterior or extensive mandibular resection and glossectomy were also independently associated with poor oral intake after surgery.ConclusionThe present study showed the positive impact of CAD/CAM mandibular reconstruction on chewing and swallowing function after surgery for locally advanced oral cancer for the first time. |
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