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早产儿脑室周围白质软化的影像学改变及其对预后的影响
引用本文:林法涛.早产儿脑室周围白质软化的影像学改变及其对预后的影响[J].国际儿科学杂志,2016(1):20-23.
作者姓名:林法涛
作者单位:1. 510623,广州医科大学附属广州市妇女儿童医疗中心新生儿科;2. 510632,暨南大学医学院生理学教研室
基金项目:广东省科技厅科技计划项目(2012B061700010)@@@@Science and Technology Planning Project of Guangdong Science and Technology Commission (2012B061700010)
摘    要:脑室周围白质软化( periventricular leukomalacia, PVL)是早产儿具有特征性的脑损伤形式之一,易造成小儿神经系统后遗症,严重影响小儿以后的运动发育和生活质量。早产儿PVL无特异性症状,诊断依赖于影像学检查。经颅超声能对PVL做出初步诊断及预后评价。结合MRI可评价PVL患儿的损伤程度,预测可能发生的不良后果,为早期治疗提供依据。该文对早产儿PVL的影像学改变及其对预后的影响进行综述。

关 键 词:早产儿  脑室周围白质软化  影像学  预后

The imaging changes of premature infants with periventricular leukomalacia and its influence on prognosis
Abstract:Periventricular leukomalacia ( PVL) is the most distinctive and characteristic brain injury in premature infants, which may result in nervous system sequelae, and affect motor development and quality of life of the infants. PVL lacks specific symptoms and the diagnosis of PVL depends on imagine. Transcranial ultrasound could make initial diagnosis and prognostic evaluation for PVL. Combined with MRI, it can assess the degree of the white matter damage and predict the possible adverse consequences, which could provide evi-dence for early treatment. The changes of brain imaging and their impact on the prognosis of PVL in preterm newborn was reviewed in this article.
Keywords:Premature infants  Periventricular leukomalacia  Imagine  Prognosis
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