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光纤药物溶出度实时测定仪监测氨茶碱片溶出度
引用本文:钟元高,张涛,廖昌军,王艳丽,何德云.光纤药物溶出度实时测定仪监测氨茶碱片溶出度[J].西南国防医药,2011,21(8):832-834.
作者姓名:钟元高  张涛  廖昌军  王艳丽  何德云
作者单位:1. 成都军区联勤部药品仪器检验所,成都,610017
2. 成都医学院药学院
摘    要:目的 比较光纤法与药典法测定氨茶碱片溶出度的利弊.方法 采用FODT -601光纤药物溶出度实时测定仪,测定某厂家8批次氨茶碱片溶出度,并与药典法测定结果进行比较.结果 光纤法测定结果普遍高于药典法,且该厂家8批次氨茶碱片间的溶出曲线差异较大.结论 光纤法溶出度可实现在线测定氨茶碱片溶出度,且能客观反映氨茶碱片溶出全过...

关 键 词:光纤药物溶出度实时测定仪  氨茶碱片  溶出度

Real-time assay of aminophylline dissolution by fiber optic dissolution test system
Zhong Yuangao,Zhang Tao,Liao Changjun,Wang Yanli,He Deyun.Real-time assay of aminophylline dissolution by fiber optic dissolution test system[J].Medical Journal of National Defending forces in Southwest China,2011,21(8):832-834.
Authors:Zhong Yuangao  Zhang Tao  Liao Changjun  Wang Yanli  He Deyun
Institution:Zhong Yuangao1,Zhang Tao1,Liao Changjun2,Wang Yanli1,He Deyun1 1.Inspection Institute of Drug and Instruments,Logistic Department of Chengdu Military Command,Chengdu,Sichuan,610017,China,2.School of Pharmaceutical Science,Chengdu Medical College,610081
Abstract:Objective To make comparison of advantages and disadvantages between fiber optic method and pharmacopia-recommended method for the assay of aminophylline tablets dissolution.Methods A fiber optic dissolution test system,FODT-601,was used to determine eight batches of aminophlline made in a domestic factory.The results were compared with those obtained by pharmacopia-recommended method.Results In general,dissolution rates of aminophylline samples assayed by fiber optic method were higher than those by pharma...
Keywords:fiber optic dissolution test system  aminophylline tablet  dissolution  
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