| 碱性成纤维细胞生长因子(bFGF)对周围神经再生作用的实验研究 |
| |
| 引用本文： | 王非,翁龙江,李主一,杨举伦,李云玫,刘大荣,蔡学敏,安梅.碱性成纤维细胞生长因子(bFGF)对周围神经再生作用的实验研究[J].西南国防医药,1999(5). |
| |
| 作者姓名： | 王非 翁龙江 李主一 杨举伦 李云玫 刘大荣 蔡学敏 安梅 |
| |
| 作者单位： | 成都军区昆明总医院全军骨科中心，成都军区昆明总医院全军骨科中心，成都军区昆明总医院全军骨科中心，成都军区昆明总医院病理科，成都军区昆明总医院神经内科，成都军区昆明总医院病理科，成都军区昆明总医院病理科，成都军区昆明总医院全军骨科中心 昆明 650032，昆明 650032，昆明 650032，昆明 650032 |
| |
| 摘 要： | 目的:探讨外源性bFGF对周围神经再生的作用。方法:6O只SD大鼠随机分治疗组、对照组各30只,钳夹损伤右侧坐骨神经后每日分别给予bFGF和生理盐水,术后行神经电生理和组织学检查。结果:计量分析治疗组运动神经传导速度、神经纤维密度、轴突直径和髓鞘厚度明显优于对照组。结论:bFGF能促进周围神经再生。
|
| 关 键 词： | 碱性成纤维细胞生长因子 周围神经 神经再生 |
EFFECT OF BASIC FIBROBLAST GROWTH FACTOR ON PERIPHERAL NERVE REGENERATION |
| |
| Wang Fei,Weng Longjiang,Li Zhuyi,Yang Julun,Li Yun-mei,Liu Darong,Cai Xuemin An Mei Orthopaedic Center of PLA,Kunming General Hospital of Chengdu Military Command,Kunming,.EFFECT OF BASIC FIBROBLAST GROWTH FACTOR ON PERIPHERAL NERVE REGENERATION[J].Medical Journal of National Defending forces in Southwest China,1999(5). |
| |
| Authors: | Wang Fei Weng Longjiang Li Zhuyi Yang Julun Li Yun-mei Liu Darong Cai Xuemin An Mei Orthopaedic Center of PLA Kunming General Hospital of Chengdu Military Command Kunming |
| |
| Institution: | Wang Fei,Weng Longjiang,Li Zhuyi,Yang Julun,Li Yun-mei,Liu Darong,Cai Xuemin An Mei Orthopaedic Center of PLA,Kunming General Hospital of Chengdu Military Command,Kunming,650032, Department of Pathology,Kunming General Hospital of Chengdu Military Command, Department of Nervous Medicine,Kunming General Hospital of Chengdu Military Command. |
| |
| Abstract: | Objective:To study the effect of exogenous basic fibroblast growth factor (bFGF) on peripheral nerve regeneration. Method: Clamped injury was made on the right sciatic nerve of 60 Sprague -Dawley rats. bFGF was injected into 30 of 60 rats as experimental group and only saline into other 30 rats as control group. All animals were observed through neuroelectrophysiological examinations and histological examinations at 1, 2, 3, 4 and 6 weeks after the operation. Result: The motor nerve conductive velocity, number of regenerating nerve fibers, thickness of myelin and diameter of ax-ons in experimental group were better than those in the control with a great difference. Conclusion: bFGF can enhance the peripheral nerve regeneration. |
| |
| Keywords: | basic fibroblast growth factor peripheral nerve regeneration |
| 本文献已被 CNKI 等数据库收录！ |
|
