PET-CT在结直肠癌肝转移诊治中的应用进展

用葡萄糖类似物18F-FDG作为显像剂的PET-CT是一种无创性显像方法,它在肿瘤尤其是转移性结直肠癌的诊断、分期、再分期、疗效监测和随访中有非常重要的作用.PET-CT融合显像将功能显像和解剖显像结合在一起,提高了全身肿瘤显像的敏感性和特异性,明显优于单独PET或CT.目前,PET-CT在结直肠癌肝转移中的应用主要是检测和甄别肝脏转移性病灶、制定治疗方案和进行疗效评价.

Progress in application of PET-CT in diagnosis and therapy of liver metastasis from colorectal cancer

PET-CT using 18F-FDG is a non -invasive imaging modality which has been recognized as the most important imaging modality in diagnosing, staging, restaging, therapy monitoring and follow-up of cancer patients, especially in metastatic colorectal cancer. PET-CT combines functional and anatomical imaging to improve sensitivity and specificity of whole-body imaging and provides incremental diagnostic value over PET or CT alone. Nowadays, applications of PET-CT imaging in liver metastasis from colorectal cancer mainly included detection and differentiation of malignant and benign liver lesions, determination of appropriate therapeutic strategies and evaluation of treatments.