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食管癌中18F-氟脱氧葡萄糖摄取和葡萄糖转运蛋白1表达的相关性研究
引用本文:王珍芳,万卫星.食管癌中18F-氟脱氧葡萄糖摄取和葡萄糖转运蛋白1表达的相关性研究[J].国际放射医学核医学杂志,2001,33(1):18-21.
作者姓名:王珍芳  万卫星
作者单位:无锡市第四人民医院、苏州大学附属第四医院核医学科,214062;
摘    要:食管癌的发生和发展涉及多个基因、分子水平的异常,是多个因素参与、共同作用的结果.18F-氟脱氧葡萄糖(18F-FDG)PET检测肿瘤细胞糖摄取在肿瘤诊断、分期、疗效评价、预后判断等方面的应用越来越广泛,而葡萄糖转运蛋白1(Glut-1)在食管癌肿瘤细胞葡萄糖摄取和细胞增殖过程中起重要作用.

关 键 词:食管肿瘤    氟脱氧葡萄糖F18    葡萄糖转运蛋白1    

Research of the relationship between expression of glucose transporter-1 and 18F-fluorodeoxyglucose uptake in esophgeal cancer
WANG Zhen-fang,WAN Wei-xing.Research of the relationship between expression of glucose transporter-1 and 18F-fluorodeoxyglucose uptake in esophgeal cancer[J].International Journal of Radiation Medicine and Nuclear Medicine,2001,33(1):18-21.
Authors:WANG Zhen-fang  WAN Wei-xing
Abstract:The occurrence and development of esophgeal cancer is a result of many factors that effect each other, which involved disorders of multiple genes and levels of molecular. The application of 18F-fluorodeoxyglucose (18F-FDG) PET detecting tumor cells glucose uptaked is more and more generally in the tumor diagnosis, staging, curative effect evaluation, and prognosis judgement and so on, glucose transporter-1 has an important role in the esophgeal cancer cells glucose uptaked and cells proliferation process.
Keywords:Esophgeal neoplasmsFluorodeoxyglucose F18Glucose transport protein-1
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