肝动脉门静脉双介入化疗栓塞治疗原发性肝癌

目的探讨肝动脉门静脉双介入化疗栓塞方法治疗原发性肝癌的可行性及临床应用。方法28例原发性肝癌患者均行超声引导下经皮穿肝至门脉造影同时行股动脉穿刺肝动脉置管造影。依据肿瘤所属肝动脉、门静脉分支的范围,数目及血流情况选择适当化疗药物和栓塞剂进行治疗。结果手术后1个月复查肿瘤均有不同程度缩小,碘油沉积大部分良好。4例患者正准备接受二期手术切除。无严重并发症出现。8例患者术后1周出现一过性肝功能异常,经保肝治疗2周后好转。结论肝动脉门静脉双介入化疗栓塞治疗原发性肝癌是安全有效的方法。

Interventional Therapy of Primary Hepatocellular Carcinoma Through Hepatic Artery and Portal Vein

Objective To investigate the clinical application in lipiodol-transcatheter arterial chemoembolization(Lp-TACE)for primary hepatocellular carcinoma(HCC) through hepatic artery and portal vein.Methods Percutaneous transhepatic portal vein angiography under ultrasound guided and hepatic artery angiography via femoral artery were performed at same time in 28 patients with HCC.The patients were treated with proper chemical medicine and embolic materials according to the feeding arteria,the extent number and blood stream of portal vein of HCC.Results One month after Lp-TACE,all of the tumors became smaller in different degree and were filled well by lipiodol.Four patients were going to undergo second stage resection of tumors.There were no severe complication.Liver function was abnormality in a short term in 8 patients and returned to mormal in two weeks after conservative treatment.Conclusion Lp-TACE for primary HCC through hepatic artery and portal vein is safe and ideal method.