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DTI 评价双侧感音神经性耳聋患儿听觉通路的价值
引用本文:赵鑫,肖宜昌,张小安,张军辉,刘祥龙,宋娟,王鑫,王雪源,赵晓艳.DTI 评价双侧感音神经性耳聋患儿听觉通路的价值[J].实用放射学杂志,2017(2).
作者姓名:赵鑫  肖宜昌  张小安  张军辉  刘祥龙  宋娟  王鑫  王雪源  赵晓艳
作者单位:1. 郑州大学第三附属医院 1 放射科;2. 耳鼻喉科,河南 郑州,450052
基金项目:河南省教育厅科学技术研究重点项目(12A310017)。
摘    要:目的:利用 MR 扩散张量成像(DTI)研究不同程度双侧感音神经性耳聋(BSNHL)患儿与正常婴幼儿听觉传导通路的差异;观察正常婴幼儿的听觉传导通路随年龄的变化。方法本院耳鼻喉门诊及住院部就诊的21例 BSNHL 患儿及24例正常婴幼儿,行 DTI 及内耳水成像扫描。用西门子后处理站测量下丘及内侧膝状体部位的各向异性分数(FA)值。根据纯音听力测试听阈值将实验组划分为甲、乙、丙3组,分别为轻度、中度、重度(本研究中包括极重度)感音神经性耳聋。轻度感音神经性耳聋的听阈为26~40 dB,中度为41~60 dB,重度为≥61 dB。结果甲组与对照组间 FA 值的差异无统计学意义(P >0.05);乙组、丙组与对照组下丘、内侧膝状体间 FA 值差异有统计学意义(P <0.05),且均小于对照组;对照组的 FA 值在2个感兴趣区(ROI)都随年龄的增长而增大。结论中度、重度 BSNHL 患儿下丘、内侧膝状体的 FA 值下降;FA 值在正常婴幼儿及轻度 BSNHL 的鉴别中价值有限。

关 键 词:双侧感音神经性耳聋  磁共振成像

The value of DTI in the diagnosis of bilateral sensorineural hearing loss
ZHAO Xin,XIAO Yichang,ZHANG Xiao an,ZHANG Junhui,LIU Xianglong,SONG Juan,WANG Xin,WANG Xueyuan,ZHAO Xiaoyan.The value of DTI in the diagnosis of bilateral sensorineural hearing loss[J].Journal of Practical Radiology,2017(2).
Authors:ZHAO Xin  XIAO Yichang  ZHANG Xiao an  ZHANG Junhui  LIU Xianglong  SONG Juan  WANG Xin  WANG Xueyuan  ZHAO Xiaoyan
Abstract:Objective Using DTI to explore the difference of auditory pathway between normal children and the patient with varying degrees of bilateral sensorineural hearing loss(BSNHL),and to observe the change of normal children’s auditory pathway with age.Methods 21 patients with BSNHL and 24 healthy children were underwent DTI and internal water imaging on Siemens 3.0T MRI.The patients with BSNHL were divided into three groups according to hearing threshold.Minor BSNHL was defined as a hearing threshold greater than 26 dB and less than 40 dB;moderate BSNHL was defined as a hearing threshold greater than 41 dB and less than 60 dB;severe BSNHL was defined as a hearing threshold greater than 61 dB.Two regions of interest (ROI)were drawn at the medial geniculate body(MGB)and the inferior colliculus (IC).The fractional anisotropy(FA)of both ROIs in all subjects were measured.Results The FA values were reduced at the MGB and the IC of patients with moderate and severe BSNHL compared with controls(P <0.05),and there was no statistical significance between the controls and patients with minor BSNHL(P >0.05).The value of FA at MGB and IC increased as the age increasing in controls.Conclusion There is reducing of FA at MGB and IC;there is low value in differentiating normal children and minor BSNHL patients.
Keywords:bilateral sensorineural hearing loss  magnetic resonance imaging
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