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化疗对恶性肿瘤患者血糖代谢的影响
引用本文:田力,杨平,聂青,李方明,吴苏冬,郑伟,朱奇.化疗对恶性肿瘤患者血糖代谢的影响[J].海军总医院学报,2008,21(1):16-18.
作者姓名:田力  杨平  聂青  李方明  吴苏冬  郑伟  朱奇
作者单位:海军总医院放疗科,北京,100037
摘    要:目的探讨化疗对恶性肿瘤患者血糖代谢的影响。方法对化疗前血糖水平正常的105例恶性肿瘤患者,追踪其化疗结束后的血糖检验报告及相关临床资料,并进行回顾性分析。结果①化疗后空腹血糖升高19例,占18.09%(19/105)。其中明确诊断为糖尿病者4例,占3.81%(4/105);糖耐量减低6例,占5.71%(6/105);一过性血糖异常升高9例,占8.57%(9/105)。②化疗诱发的血糖异常多发生在化疗的第1~3个疗程。③以紫杉醇合并铂类化疗后血糖升高为著(20%)。④不同肿瘤化疗后血糖异常升高发生率无差异(P〉0.05)。结论恶性肿瘤患者接受化学药物治疗后可能会出现血糖异常,甚至发生糖耐量减低或糖尿病,尤以紫杉醇合并铂类化疗影响为著,应引起重视。

关 键 词:肿瘤  紫杉醇  血糖  糖尿病
文章编号:1009-3427(2008)01-0016-03
修稿时间:2007年11月16

Study on Chemotherapy Induced Disorders of Glucose Metabolism in Patients with Malignant Tumors
TIAN Li,YANG Ping,NIE Qing,LI Fang-ming,WU Su-dong,ZHENG Wei,ZHU Qi.Study on Chemotherapy Induced Disorders of Glucose Metabolism in Patients with Malignant Tumors[J].Journal of Naval General Hospital of PLA,2008,21(1):16-18.
Authors:TIAN Li  YANG Ping  NIE Qing  LI Fang-ming  WU Su-dong  ZHENG Wei  ZHU Qi
Institution:TIAN Li,YANG Ping,NIE Qing,LI Fang-ming,WU Su-dong,ZHENG Wei,ZHU Qi(Department of Radiation Oncology,Naval General Hospital,Beijing 100037,China)
Abstract:Objective To observe the effect of chemotherapy on glucose metabolism in patients with malignant tumors.Methods The blood glucose assay and associated clinical materials of 105 cases with malignant tumors who received chemotherapy from June 2003 to June 2006 were analyzed retrospectively.Results Nineteen cases had elevated fasting blood glucose after chemotherapy.Among them,4 cases were diagnosed as diabetes mellitus,6 cases were diagnosed as impaired glucose tolerance,9 cases were diagnosed as temporarily ...
Keywords:Malignant tumor  Paclitaxel  Blood glucose  Diabetes mellitus  
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