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人皮移植于裸小鼠体上的实验模型
引用本文:耿建兵,陈起展.人皮移植于裸小鼠体上的实验模型[J].军事医学科学院院刊,1989,13(3):221-224.
作者姓名:耿建兵  陈起展
作者单位:军事医学科学院毒物药物研究所,军事医学科学院毒物药物研究所,军事医学科学院毒物药物研究所,军事医学科学院附属医院
摘    要:本文报道了人皮移植到裸鼠背部的实验模型.通过肉眼及组织学检查,人皮片可活存3个月之久.在皮片移植约1个月后,此模型可用于皮肤药理学和皮肤毒理学的研究.文中简要地讨论了皮片厚度、皮肤创面的固定及包扎和皮片的保护等有关技术问题.

关 键 词:人皮移植  裸鼠  实验模型

AN EXPERIMENTAL MODEL OF HUMAN SKIN GRAFTING ON NUDE MOUSE
Geng Jianbing,Chen Qizhan,Xu Xiaoshan,Yang Zhixiang Institute of Toxicology and Pharmacology,Academy of Military Medical Sciences.AN EXPERIMENTAL MODEL OF HUMAN SKIN GRAFTING ON NUDE MOUSE[J].Bulletin of the Academy of Military Medical Sciences,1989,13(3):221-224.
Authors:Geng Jianbing  Chen Qizhan  Xu Xiaoshan  Yang Zhixiang Institute of Toxicology and Pharmacology  Academy of Military Medical Sciences
Abstract:An experimental model of human skin grafting on nude mouse back is reported.The grafted skin flaps were examined with naked eyes and histological methods,and might survive for 3 months Approximately 1 month after human skin grafting this model may be used for dermato-pharmacological and dermato-toxicological studies.The thickness of skin flap to be used,the immobilization and bandaging of the skin wound and the protection of the grafted skin flap are discussed briefly.
Keywords:experimental model  nude mouse  human skin graft
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