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最小相对表观弥散系数值在低级别胶质瘤与反应性胶质增生鉴别诊断中的价值
引用本文:胡步宏,贾中正,耿道颖.最小相对表观弥散系数值在低级别胶质瘤与反应性胶质增生鉴别诊断中的价值[J].中国医学计算机成像杂志,2011,17(3).
作者姓名:胡步宏  贾中正  耿道颖
作者单位:复旦大学附属华山医院放射科
摘    要:目的:探讨低级别胶质瘤与反应性胶质增生中最小相对表观弥散系数值(rADCmin)的鉴别诊断价值.方法:病理证实的低级别胶质瘤(WHO Ⅱ级)58例与反应性胶质增生11例纳入研究,所有患者术前进行常规MRI和弥散加权成像(DWI),测量病变的rADCmin值并比较其在两种病理状态中的差异,计算用rADCmin诊断低级别胶质瘤的临界值、敏感性和特异性.结果:低级别胶质瘤的平均rADCmin(1.465±0.357)大于反应性胶质增生的1.062±0.120(P<0.05),ROC曲线分析显示当rADCmin=1.193时,敏感性为82.8%,特异性为100%.结论:rADCmin在低级别胶质瘤与反应性胶质增生的鉴别诊断中能够提供诊断价值.

关 键 词:表观弥散系数  弥散加权成像  胶质瘤  反应性胶质增生

Differentiation of Low- grade Glioma and Reactive Gliosis: Diagnostic Value of Minimum Relative Apparent Diffusion Coefficient
HU Bu-hong,JIA Zhong-zheng,GENG Dao-ying.Differentiation of Low- grade Glioma and Reactive Gliosis: Diagnostic Value of Minimum Relative Apparent Diffusion Coefficient[J].Chinese Computed Medical Imaging,2011,17(3).
Authors:HU Bu-hong  JIA Zhong-zheng  GENG Dao-ying
Institution:HU Bu-hong,JIA Zhong-zheng,GENG Dao-ying Department of Radiology,Huashan Hospital,Fudan University12 Wulumuqi Middle Rd.,Shanghai 200040,P.R.C.
Abstract:Purpose: To evaluate the diagnostic value of minimum relative apparent diffusion coefficient(rADCmin) for the differentiation of low-grade glioma and reactive gliosis.Methods:Fifty-eight cases of low-grade glioma and 11 cases of reactive gliosis were enrolled in this study.All patients had preoperatively undergone conventional MRI and diffusion weighed imaging(DWI).The rADCmin values were measured and were evaluated regarding statistical differences between low-grade glioma and reactive gliosis.A receiver o...
Keywords:Apparent diffusion coefficient  Diffusion weighted imaging  Glioma  Reactive gliosis  
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