上消化道溃疡、炎症性病变再生修复的临床研究

目的：观察美宝胃肠胶囊对上消化道溃疡生理愈合治疗作用及炎症性病变的疗效,寻找上消化道溃疡、炎性疾病的理想治疗方法。方法：选择经电子胃镜检查诊断为上消化道溃疡、炎症性病变病例62例,根据自愿原则,其中20例单独服用美宝胃肠胶囊(实验A组),12例服用美宝胃肠胶囊同时加服雷尼替丁(实验B组),其余30例用现行的内科治疗药物治疗(对照组),观察并比较治疗一个月的效果。结果：治疗10天,实验A组和B组病人自觉症状、体征消失(优秀)率分别为95．5%和100．0%,对照组为73．3%；治疗20天症状、体征消失(优秀)率：实验A组与B组均为100．0%,对照组为76．7%；自觉症状体征消失与改善率均高于对照组(P＜0．005)；治疗一个月复查胃镜下A组十二指肠溃疡生理性愈合率94．1%,明显高于对照组(P＜0．05),和炎症病变好转率组间无明显差异(P＜0．05)。结论：美宝胃肠胶囊可有效改善或缓解早期临床症状,促进胃、十二指肠溃疡生理性愈合；美宝胃肠胶囊不仅是维护胃肠黏膜正常的一种保健药物,它对胃、十二指肠溃疡具有良好的治疗作用。

Clinical research on regenerative repair of upper digestive tract ulcer and inflammatory pathologic change

Objective： To observe the efficacy of MEBO Gastrointestinal Capsule in regenerative repair of upper digestive tract ulcer and inflammatory pathologic change. Method： 62 patients were diagnosed by gastroscopy to be suffering from upper digestive tract ulcer and inflammatory pathologic change. According to their own will, 20 of them were treated with MEBO Gastrointestinal Capsule alone （experiment group A）, 12 of them were treated with MEBO Gastrointestinal Capsule in combination with ranitidine （ experiment group B） and 30 of them treated with other medicine （ control group）. The patients in the 3 groups were treated respectively for 30 days and the efficacy was compared. Result： After 10 days of treatment, patients in group A and B had subjective symptom and physical sign vanished. The markedly effective rates were respectively 95.5% and 100%, while in control group, the markedly effective rate was 73.3%. After 20 days of treatment, the markedly effective rates in group A and group B were 100% and in control group 76. 7%. In groups A and B, the effective rates of improving subjective symptom and physical sign were higher than that in control group （ P 〈 0. 005 ）. After 30 days of treatment, patients in group A had duodenal ulcers physiologically healed and inflammatory changes vanished as examined by gastroscopy. This result was better than that in control group （P 〈0. 05）. Conclusion： MEBO Gastrointestinal Capsule can effectively improve the clinical symptom and promote physiological healing of gastric and duodenal ulcers. It is not only a health care remedy for protecting normal mucous membrane of stomach and intestine, but also a good medicine for treating gastric and duodenal ulcers.