磁共振弥散加权成像在新生儿缺氧缺血性脑病的诊断价值

目的:以磁共振弥散加权成像(DWI)技术并与常规MR T1WI、T2WI结合应用,探讨DWI对新生儿缺氧缺血性脑病(HIE)的早期诊断价值。方法:对我院2004年1月~2010年1月临床确诊缺氧缺血性脑病的新生儿62例(4h~15天)进行DWI和常规T1WI、T2WI检查。结果:DWI出现高信号病灶59例,T1WI信号异常32例,T2WI信号异常13例。DWI高信号病灶多见于大脑皮层、侧脑室周围白质区及室管膜下,T1WI高信号以脑室周围白质区多见。出血性病变,在T1WI呈高信号,而DWI表现为无信号。结论:DWI适用于早期HIE,T1WI及T2WI在亚急性期、恢复期或随访应用显示病灶较好。

Diagnostic value of MR diffusion-weighted imaging in neonatal hypoxic-ischaemic encephalopathy

Objective：Using the MR diffusion-weighted imaging（DWI） technique associated with the routine MR T1WI、T2WI,to study the early diagnostic value of DWI in neonatal hypoxic-ischaemic encephalopathy（HIE）.Methods：During the period from January 2004 to January 2010,62 neonatal clinical definited HIE were examined using DWI and routine T1WI、T2WI.Results：59 cases had high signal intensity（SI） on DWI sequences,32 cases had abnormal SI on T1WI,13 cases had abnormal SI on T2WI,high SI changes on DWI were usually limited to the cerebral cortex,periventricular white matter and subendyma.High SI on T1WI were usually seen in periventricular white matter.Hemorrhagic affection shows high SI on T1WI and no SI on DWI.Conclusion：DWI are applied to early HIE,T1WI and T2WI sequence shows the affection better in subacute,chronic phase or follow up application.