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高原青年移居者凝血纤溶系统的研究
引用本文:雷应权,彭顺舟,冯国君,任雨笙.高原青年移居者凝血纤溶系统的研究[J].高原医学杂志,2004,14(3):29-30.
作者姓名:雷应权  彭顺舟  冯国君  任雨笙
作者单位:西藏乃东解放军第41医院,856000;上海第二军医大学长征医院心内科,210000
摘    要:目的 :研究高原青年移居者血液凝血纤溶系统的状态。方法 :检测 38例青年移居者血浆组织型纤溶酶原激活物 (t -PA)、纤溶酶原激活物抑制剂 (PAI)和纤维蛋白原 (Fbg)含量 ,并与 36例健康藏族世居青年进行比较。以平原健康青年作为对照。结果 :移居者较藏族世居组及对照组t -PA活性降低 (P <0 .0 5 ) ,PAI活性增高 (P <0 .0 5 ) ,各组之间Fbg含量无显著性差别 (P >0 .0 5 )。结论 :高原青年移居者血液处于高凝状态。

关 键 词:凝血纤溶系统  移居  高原

Study of Fibrinolysis System in Young Migrants Exposed to High Altitude
Lei Yingquan,Peng Shunzhou,Feng Guojun,Ren Yusheng The st Hospital of PLA.Study of Fibrinolysis System in Young Migrants Exposed to High Altitude[J].Journal of High Altitude Medicine,2004,14(3):29-30.
Authors:Lei Yingquan  Peng Shunzhou  Feng Guojun  Ren Yusheng The st Hospital of PLA
Institution:Lei Yingquan,Peng Shunzhou,Feng Guojun,Ren Yusheng The 41st Hospital of PLA
Abstract:Objective: To study the changes of the fibrinolysis coagulation system in young migrants exposed to high altitude.Methods: Plasma level of tissue-type plasminogen activator (t-PA), plasminogen activator inhibior-1 (PAI-1) and fibrinongen (Fbg) were measured in 38 migrants and compared the results with 36 healthy native Tibetans; the healthy subjects at plain served as the control.Results: The level of activity of t-PA was lower in migrants than that in Tibetans(P<0.05). The activity of PAI-1 in migrants was higher than that in the Tibetans(P<0.05).Conclusion: The study indicated there was a state apt to coagulation in migrants.
Keywords:Fibrinolysis coagulation system  Migrant  High altitude
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