| 一种新型失血性休克动物模型和初级生命救护装置的联合实验和评价 |
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| 引用本文： | 郑军,洪波,张世范,杨俊峰,徐迪辉,高明,孟辉,林勤燕,唐娜.一种新型失血性休克动物模型和初级生命救护装置的联合实验和评价[J].西北国防医学杂志,2010,31(2):86-88. |
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| 作者姓名： | 郑军 洪波 张世范 杨俊峰 徐迪辉 高明 孟辉 林勤燕 唐娜 |
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| 作者单位： | 1. 广州军区疗养院康复急救中心,广东,广州,510515
2. 兰州军区兰州总医院胸外科 |
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| 基金项目： | 全军"十五"重点科研基金资助项目 |
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| 摘 要： | 目的：研制创伤失血性休克动物模型,评价系列救护装置应用效果。方法：健康比格犬18只,随机分为微创假休克组（A组,n=6）、重创失血性休克自体输血组（B组,n=6）和重创失血性休克非自体输血组（C组,n=6）。A、C组常规液体复苏;B组用自制救护装置自体输血复苏。结果：血像、生化指标B、C两组最重,B〉C〉A。P≤0.05;但胸腔血RBC、WBC、PLT、HGB仍在正常范围内;PaO2C、A组伤后2-24 h呈阶梯性下降至低氧血症水平,但B组仍在正常范围,P〈0.05。用自制新系列装置进行急性胸腔闭式引流、自体输血可在3~5 min内完成技术操作,优于同类市售装置,B组动物全部成活,C组半数死亡。结论：梿枷胸失血性休克模型成功率高,可重复性强,自制初级生命救护装置实用性强,性能稳定,值得进一步推广。
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| 关 键 词： | 失血性休克 动物模型 胸腔闭式引流 自体输血 一线救护装置 |
Experimental observation and evaluation of a new-type traumatic-hemorrhagic shock model and first-aid life supporting devices |
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| ZHENG Jun,HONG Bo,ZHANG Shi-fan,et al..Experimental observation and evaluation of a new-type traumatic-hemorrhagic shock model and first-aid life supporting devices[J].Medical Journal of National Defending Forces in Northwest China,2010,31(2):86-88. |
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| Authors: | ZHENG Jun HONG Bo ZHANG Shi-fan |
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| Institution: | ZHENG Jun,HONG Bo,ZHANG Shi-fan,et al.(Rehabilitation , Emergency Rescuing Center,Guangzhou Convalescent Hospital,Guangzhou Comm,,PLA,Guangzhou 510515,China) |
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| Abstract: | Objective: To establish a new-type traumatic-hemorrhagic shock model and research the effect of self-made serial first-aid life supporting devices.Methods: Eighteen Beagle dogs were randomly divided into 3 groups: group A(mild hemorrhagic shock models resuscitated with NS,n=6),group B(severe hemorrhagic shock models resuscitated by autotransfusion,n=6) and group C(severe hemorrhagic shock models resuscitated with NS,n=6).Results: The CK,GOT and WBC sharply increased after 2-4 hours in all groups(group B>C>A... |
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| Keywords: | Hemorrhagic shock Animal models Closed chest drainage Autotransfusion First-aid devices |
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