| THP和MMC膀胱内灌注治疗浅表性膀胱癌疗效观察 |
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| 引用本文： | 张见超,钟修龙,赵阳,李延江.THP和MMC膀胱内灌注治疗浅表性膀胱癌疗效观察[J].中国航天工业医药,2010(11):18-20. |
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| 作者姓名： | 张见超 钟修龙 赵阳 李延江 |
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| 作者单位： | 青岛大学医学院附属医院泌尿外科,266003 |
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| 摘 要： | 目的评价吡柔比星（THP）、丝裂霉素C（MMC）两种药物膀胱灌注治疗浅表性膀胱癌的不同疗效。方法将64例浅表性膀胱癌随机分为两组,分别用THP和MMC作膀胱灌注治疗药物,观察其不同疗效。结果所有病例随访3～24个月,平均14个月。THP组复发率11.76%（4/34）,MMC组复发率23.33%（7/30）,差别具有统计学意义（P〈0.05）。结论 THP膀胱灌注防治浅表性膀胱癌术后复发的疗效优于MMC,可作为临床一线用药。
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| 关 键 词： | 膀胱癌 吡柔比星 丝裂霉素C 膀胱灌注 |
Observation of the effect of pirarubicin and mitomycin-C bladder instillation to treat bladder cancer on prevention the recurrence after operation |
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| Institution: | Zhang Jianchao,Zhong Xiulong,Zhao Yang,et al.(Department of Urology,Affiliated Hospital of Medical College,Qingdao University,Qingdao 266003 ) |
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| Abstract: | Objective To evaluate the effect of THP and MMC by bladder instillation to treat superficial bladder cancer.Methods A total of 64 patients with superficial bladder cancer were divided into 2 groups randomly.THP by bladder instillation was used in the first group,MMC in the second group.The effects were observed.Results All patients were followed up 3～24 months.The tumor recurrent rate in the THP group and MMC group were 11.76%（4/34） and 23.33%（7/30）.The tumor recurrent rate of the THP groups differed significantly from the MMC group（P〈0.05）.Conclusion The curative effect of THP to prevent the recurrence of superficial bladder cancer is superior to that of MMC.THP is the first choice in clinical bladder instillation. |
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| Keywords: | Bladder tumor THP MMC Bladder instillation |
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