伊曲康唑联合甲床修整术治疗重症甲真菌病的疗效观察

目的观察口服伊曲康唑联合甲床修整术治疗重症甲真菌病的临床疗效。方法将140例甲真菌病患者随机分为两组,治疗组68例采用甲床修整术联合口服伊曲康唑治疗;对照组72例单纯口服伊曲康唑治疗。结果治疗组痊愈率及总有效率分别为70.6%及88.2%,对照组分别为45.8%及65.2%,两组患者痊愈率及总有效率差异均有显著统计学意义(P<0.01)。结论伊曲康唑口服联合甲床修整术治疗重症甲真菌病疗效高,能显著改善新甲的生长速度及外观。

Efficacy observation of Itraconazole and nail bed dressing surgery in the treatment of severe onychomycosis

Objective To observe the clinical efficacy of combined therapy of oral itraconazole and nail bed dressing surgery in the treatment of severe onychomycosis.Methods Totally 140 patients with onychomycosis were randomly divided into treatment and control groups.The 68 patients in treatment group accepted the therapy of combined therapy of oral itraconazole and nail bed dress-ing surgery,while the 72 patients in control group were treated with itraconazole alone.Results The cure rate and total effective rate of treatment group were 70.6% and 88.2%,while of the contrast group were 45.6% and 65.2%.The differences of cure rate and total effective rate between the two groups showed statistical significance(P<0.01).Conclusion Combined therapy of oral Itraconazole and nail bed dressing surgery significantly is effective and can improve the growth rate and appearance of the new nail.