| 妊高征患者血浆氧化修饰低密度脂蛋白水平及其临床意义 |
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| 引用本文： | 马景德,齐秀芬,安慧美,高云,王叶杰.妊高征患者血浆氧化修饰低密度脂蛋白水平及其临床意义[J].临床军医杂志,2003,31(5):41-43. |
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| 作者姓名： | 马景德 齐秀芬 安慧美 高云 王叶杰 |
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| 作者单位： | 解放军第106医院,山东,济南,250022 |
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| 摘 要： | 目的 探讨妊高征患者血浆中氧化修饰低密度脂蛋白(ox-LDL)的水平及其在妊高征发病中的作用。方法 用ELISA方法检测了44例妊高征患者(妊高征组)和34例同期正常孕妇(对照组)血浆中ox-LDL的含量。结果 妊高征轻、中、重度患者ox-LDL的含量分别为(0.42±0.21)mg/L,(0.54 ±0.33)mg/L和(0.68±0.37)mg/L,明显高于对照组的(0.35±0.12)mg/L(P<0.01)。结论 ox-LDL增加可能是妊高征患者血管内皮细胞损伤的原因之一,可作为妊高征的监测指标之一。
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| 关 键 词： | 妊娠并发症 心血管 高血压 氧化修饰低密度脂蛋白 |
| 文章编号： | 1671-3826(2003)05-0041-03 |
| 修稿时间： | 2003年8月11日 |
The Plasma Level of Oxidatively Modified Low Density Lipoprotein in Patients with Pregnancy Induced Hypertension Syndrome and Its Clinical Significance |
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| Ma Jing-de,Qi Xiu-fen,An Hui-mei,Gao Yun,Wang Ye-jie.The Plasma Level of Oxidatively Modified Low Density Lipoprotein in Patients with Pregnancy Induced Hypertension Syndrome and Its Clinical Significance[J].Clinical Journal of Medical Officer,2003,31(5):41-43. |
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| Authors: | Ma Jing-de Qi Xiu-fen An Hui-mei Gao Yun Wang Ye-jie |
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| Abstract: | Objective To explore the plasma level of oxidatively modified low density lipoprotein (ox-LDL) in patients with pregnancy induced hypertension (PIH) and its clinical significance. Methods 44 cases with PIH and 34 normal pregnancy with the same pregnancy weeks were detected for ox-LDL by ELISA. Results The plasma levels of ox-LDL in mild , moderate , severe PIH is (0.42±0.21) mg/L, (0.54±0.33) mg/L and (0.68 ±0.37) mg/L, respectively, significantly higher than that in control group ( 0.35±0.12) mg/L (P < 0.01). Conclusion The higher ox-LDL may be one of the causes for endothelial cell damage in PIH and can be used as a predicting index. |
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| Keywords: | pregnancy complications cardiovascular hypertension oxidatively modified low density lipoprotein |
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