| 神经黑色素敏感的MRI在帕金森病中的应用进展 |
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| 引用本文： | 柏福运,高平.神经黑色素敏感的MRI在帕金森病中的应用进展[J].国际医学放射学杂志,2021,44(2):165-169. |
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| 作者姓名： | 柏福运 高平 |
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| 作者单位： | 湖北医药学院附属襄阳市第一人民医院放射科,湖北省帕金森病临床医学研究中心,襄阳441000 |
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| 基金项目： | 湖北省卫计委科研计划项目(WJ2017M231)。 |
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| 摘 要： | 帕金森病（PD）以含神经黑色素的儿茶酚胺类神经元进行性坏死为病理特征。神经黑色素敏感磁共振成像（NM-MRI）可以检测颅内神经黑色素的含量,从而对PD进行诊断、鉴别诊断、亚型评估及病情监测。目前PD NM-MRI的临床应用基于不同的成像技术及数据分析方法,包括不同的成像序列、成像维度、磁场强度及评估对象、评估指标、数据分析方法等。就NM-MRI的成像技术、PD的临床应用及其不同的数据分析方法予以综述。
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| 关 键 词： | 神经黑色素 帕金森病 磁共振成像 |
| 收稿时间： | 2020-06-18 |
The advance of neuromelanin sensitive magnetic resonance imaging in Parkinson’s disease |
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| BAI Fuyun,GAO Ping.The advance of neuromelanin sensitive magnetic resonance imaging in Parkinson’s disease[J].International Journal of Medical Radiology,2021,44(2):165-169. |
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| Authors: | BAI Fuyun GAO Ping |
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| Institution: | Department of Radiology, Xiangyang First People’s Hospital, Hubei University of Medicine, Hubei Clinical Research Center for Parkinson’s diesease, Xiangyang 441000, China |
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| Abstract: | The pathological feature of Parkinson’s disease(PD)is progressive necrosis of catecholamine neurons which containing neuromelanin.Neuromelanin sensitive magnetic resonance imaging(NM-MRI)can detect the intracranial neuromelanin content,thus can make the diagnosis,differential diagnosis,subtype assessment and monitoring disease progress of PD.At present,the clinical application of NM-MRI in PD is based on different imaging technologies and data analysis methods,including imaging sequences,imaging dimensions,magnetic field intensity,evaluation objects,evaluation indicators,data analysis methods,etc.The imaging technology of NM-MRI,clinical application in evaluation of PD,and different data analysis methods were reviewed. |
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| Keywords: | Neuromelanin Parkinson’s disease Magnetic rosanance imaging |
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