计算机辅助设计医用树脂和羟基磷灰石复合人工骨材料在颅骨修补术中的应用

目的 探讨应用计算机辅助成形后医用树脂(epoxide acrylate maleic,E)和羟基磷灰石(hydroxyapatite,H)复合人工骨材料(EH)在颅骨修补术中的作用.方法 采用EH型复合人工骨材料,计算机辅助设计、制造出个体化颅骨瓣,对45例患者进行颅骨修补手术,并随访观察6个月～3年.结果 本组45例患者中,术后发生皮下积液1例,骨瓣轻度塌陷1例.其余无感染及排异反应,且外形修复精致.结论 采用EH型复合人工骨材料,术前应用计算机辅助塑形后具有匹配良好、术中节省手术时间、术后随访表现出生物相容性好等优点,可提高临床疗效.

Clinical application of computer-aided design of composite materials with epoxide acrylate maleic and hydroxyapatite in cranioplasty

Objective To evaluate the effect of computer-aided design of composite materials with epoxide acrylate maleic (E) and hydroxyapatite (H) in cranioplasty. Methods A total of 45 patients with cranium defects were treated with cranioplasty by using skull bone flaps made of composite materials including epoxide acrylate maleic (E) and hydroxyapatite (H) ,which was designed with computer aid according to individual requirements. The patients were followed up for 6-36 months. Results After cranioplasty with composite EH, there occurred subcutaneous fluid in one patient and mild bone collapse in one. The composite EH showed good histocompatibility, with no infection or rejection. Conclusion During cranioplasty, use of computer-aided design of composite EH takes advantages of good accuracy, short operation time, good biocompatibility and good clinical efficiency.