| CT引导下经皮射频消融治疗较大原发性肝癌的临床应用 |
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| 引用本文： | 郑云峰,陈克敏,王忠敏,贡桔,赵正兴,顾丽娟.CT引导下经皮射频消融治疗较大原发性肝癌的临床应用[J].介入放射学杂志,2009(5). |
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| 作者姓名： | 郑云峰 陈克敏 王忠敏 贡桔 赵正兴 顾丽娟 |
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| 作者单位： | 1. 上海交通大学医学院附属瑞金医院卢湾分院放射科,200020
2. 瑞金医院放射科 |
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| 摘 要： | 目的 探讨CT引导下经皮射频消融(RFA)治疗较大原发性肝癌的疗效.方法 对27例TACE治疗效果欠佳的较大原发性肝癌患者行CT引导下经皮RFA治疗,肿瘤大小5.4-11.0 cm,平均6.2 cm.单发病灶23例,2个病灶4例,共31个病灶.AFP阳性22例.术后通过增强CT及AFP检测评价疗效,所有病例随访2～20个月.结果 射频治疗后1个月随访显示,31个肿瘤中14个(45.2%)肿瘤完全坏死,内部及边缘无明显强化;17个肿瘤部分坏死.22例AFP阳性患者,AFP明显降低15例(68.2%),不变3例(13.6%),升高4例(18.2%).并发症中3例出现表皮烫伤,1例顽固性呃逆,1例肝内出血,1例肝脓肿,1例术后出现严重低蛋白血症,术后2个月死亡.患者中位生存期为9.8个月,1年累计生存率29%.结论 对于不可切除的较大原发性肝癌,RFA是较有效的局部介入治疗方法,合理应用RFA治疗,可提高患者生活质量并延长患者的生存时间.
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| 关 键 词： | 射频消融 肝癌 CT引导 |
Clinical application of CT-guided percutaneous radiofrequency ablation for the treatment of larger hepatocellular carcinomas |
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| ZHENG Yun-feng,CHEN Ke-min,WANG Zhong-min,GONG Ju,ZHAO Zheng-xin,GU Li-juan.Clinical application of CT-guided percutaneous radiofrequency ablation for the treatment of larger hepatocellular carcinomas[J].Journal of Interventional Radiology,2009(5). |
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| Authors: | ZHENG Yun-feng CHEN Ke-min WANG Zhong-min GONG Ju ZHAO Zheng-xin GU Li-juan |
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| Institution: | ZHENG Yun-feng,CHEN Ke-min,WANG Zhong-min,GONG Ju,ZHAO Zheng-xin,GU Li-juan.Department of Radiology,Luwan Branch of Ruijin Hospital,School of Medicine,Shanghai Jiaotong University,Shanghai 200020,China |
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| Abstract: | Objective To investigate the therapeutic efficacy of CT-guided percutaneous radiofrequency ablation(RFA) for the larger hepatocellular carcinomas.Methods CT-guided RFA was performed in 27 patients with larger hepatocellular carcinoma(total of 31 lesions),who showed poor response to transcatheter arterial chemoembolization(TACE) treatment.The diameter of the lesions was 5.4-11 cm,with a mean diameter of 6.2 cm.Positive AFP was detected in 22 patients.The therapeutic efficacy was evaluated with enhanced CT sc... |
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| Keywords: | radiofrequency ablation hepatocellular carcinoma CT-guidance |
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