肝动脉化疗栓塞治疗原发性肝癌中碘油沉积良好患者疗效观察

目的：评价肝动脉化疗栓塞治疗原发性肝癌中碘油沉积良好患者疗效。:方法：采用Kaplan-Meier统计学方法对144例碘油沉积良好的原发性肝癌患者进行回顾性分析，计算其生存率。结果：144例患者总体1、2、3、4、5年生存率分别为85．0％、 63．7％、51．7％、33．9％、16．9％。与本科报道的肝癌总体生存率比较，1、2、3、4年生存率有显著性差异（P＜0．001），5年生存率无明显差异（P＝0．88）。结论：肝TACE治疗中肝瘤内碘油沉积良好能提高肝癌患者近期的治疗效果和1、2、3、4年生存率,但5年以后的远期疗效欠佳。肝TACE治疗的同时需对患者进行综合治疗才能进一步提高疗效。

The clinical effect in patients with primary liver cancer with well filled lipiodol after transcatheter arterial chemoembolization

Objective To evaluate the clinical effect in patients with primary liver cancer (PLC) well filled with Lipiodol after transcatheter arterial chemoembolization (TACE). Methods 144 patients with PLC well filled with lipiodol after TACE were analysed retrospectively, and the survival rates were calculated by Kaplan Meier method. Results The overall cumulative survival rates for 1,2,3,4 and 5 year were 85.0%, 63.7%, 51.7%, 33.9% and 16.9% respectively. Significant differences were found for 1,2,3 and 4 year survival rates and that of 400 patients with PLC treated by TACE reported previously by our department ( P <0.001), but the 5 year survival rate showed no difference ( P =0.88). Conclusions Well filled with lipiodol in the tumor after TACE can improve the short term therapeutic effect and the 1,2,3 and 4 year survival rate of patients with PLC. The long term therapeutic effect is poor yet. Integrative treatment is needed to make further improvement on the therapeutic effect.