| 1,6-二磷酸果糖治疗新生儿窒息后心肌损害 |
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| 引用本文： | 崔明辰.1,6-二磷酸果糖治疗新生儿窒息后心肌损害[J].儿科药学杂志,2007,13(3):51-52. |
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| 作者姓名： | 崔明辰 |
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| 作者单位： | 漯河医学高等专科学校第三附属医院,河南漯河,462002 |
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| 摘 要： | 目的:观察1,6-二磷酸果糖(FDP)对新生儿窒息后心肌损害的治疗作用及效果.方法:74例窒息后心肌损害患儿随机分为治疗组38例,对照组36例.对照组采用常规治疗,治疗组在常规治疗的基础上加用FDP.比较两组疗效及临床症状消失、心率变化、ECG恢复、CK-MB改善及心衰纠正情况.结果:总有效率治疗组92.11%,对照组69.44%,两组比较差异有统计学意义(P＜0.05);治疗组在临床症状消失、ECG恢复、CK-MB改善、心衰纠正的时间等方面均较对照组缩短,差异有统计学意义(P＜0.01).结论:FDP对新生儿窒息后心肌损害有积极的、确切的治疗作用,可改善心肌能量代谢,促进心肌缺氧损伤恢复.保护心脏功能.
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| 关 键 词： | 1 6-二磷酸果糖 新生儿 窒息 心肌损害 |
| 文章编号： | 1672-108X（2007）03-0051-02 |
| 修稿时间： | 2006-12-152007-01-29 |
A study on 1,6-fructose diphosphate in treating cardiac damage after neonatal asphyxia |
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| CUI Ming-chen.A study on 1,6-fructose diphosphate in treating cardiac damage after neonatal asphyxia[J].Journal of Pediatric Pharmacy,2007,13(3):51-52. |
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| Authors: | CUI Ming-chen |
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| Institution: | The Third Affiliated Hospital of The Luohe Medical College, Henan Luohe 462002, China |
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| Abstract: | objective:To observe the effect ot 1,6-Iuctose diphosphate(FDP)in treating cardiac damage after neonatal asphyxia.Methods:74 patients were randomly divided into the treatment group(n=38)and the control group(n=36).To the treatment group,FDP was given in addit- ion to routine therapy.The effecta of the two groups were observed and compared on symptom disappearing,heart rate changing,ECG recovering, CK-MB improving and heart failure rectifying.Results:The total effective rate of the treatment group was 92.11% and the control group 69.44%. The treatment group were distinctly better than the control group(P<0.05).The treatment group excelled the control group in these aspects and notable difference was detected(P<0.01 ).Conclusions:FDP has obvious effects in ameliorating the metabolism of cardiac muscle,accelerating the repairing for anoxic cardiac muscle and protecting the heart. |
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| Keywords: | 1 6-Fructose diphosphatc Neonate Asphyxia Cardiac damage |
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