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Synthesis,Molecular Docking and Biological Evaluation of Diaryl Pyrimidine Derivatives as Urease Inhibitors |
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| Authors: | Boumi Sh Talebi M Sarmad Y Bassam K Barzegar M Hosseini F S Amini M Amanlou M |
| Institution: | 1.Department of Medicinal Chemistry, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran ;2.Experimental Medicine Research Center, Tehran University of Medical Sciences, Tehran, Iran ; |
| Abstract: | Pharmaceutical Chemistry Journal - Urease is a dinickel enzyme that is responsible for the hydrolysis of urea to ammonia and carbon dioxide. A series of bacteria like Helicobacter pylori produce... |
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