多b值磁共振扩散加权成像在前列腺良、恶性结节中的对比研究

目的：通过对前列腺结节多b值的定量分析研究，探讨评价DWI对前列腺良、恶性结节的临床应用价值。方法回顾性分析经手术及病理证实的36例前列腺结节的常规MRI及DWI征象，分别测量在多b值条件下良、恶性结节的表观扩散系数（ADC），并讨论不同b值的应用价值。结果本组36例患者中，良性结节25例，恶性结节11例。采用b值（200、400、600、800、1000s/mm2）时良性组与恶性组之间ADC值的差异均有统计学意义（P<0.05）。结论前列腺良性结节的ADC值高于恶性结节，在多b值的扩散加权成像中，尤其以b值取800 s/mm2时，鉴别良、恶性结节的效能最高，有助于前列腺结节性质的判断和鉴别，对其术前诊断分期、术后治疗方案的设计制定，都有着十分重要的指导意义。

Comparison of Multiple b Values of Magnetic Resonance Diffusion Weighted Imaging in Benign and Malignant Nodules of Prostate

objective To evaluate the clinical value of DWI in benign and malignant prostate nodules by quantitative analysis of B value of prostate nodules.Methods Retrospective analysis of the surgery and pathology of 34 patients with prostate nodules of conventional MRI and DWI findings were measured in B value table of benign and malignant nodules under the condition of appar-ent diffusion coefficient (ADC),and to discuss the application value of different b values.Results Among the 36 cases,25 cases were benign and 11 were malignant.The difference of ADC value between benign and malignant groups was statistically significant (P<0.05)when the b value was(200,400,600,800,1000s/mm2).Conclusion Prostate benign nodules of ADC value is higher than that of malignant nodules,in B value diffusion weighted imaging,especially the b value take 800 s/mm2,the effectiveness of differen-tial diagnosis of benign and malignant nodules,with the highest help on the judgment and identification of prostate nodules,preoper-ative diagnosis staging,postoperative treatment scheme design formulation,have a very important significance.