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帕瑞昔布钠用于老年患者前列腺电切术后镇痛及对肾功能的影响
引用本文:崔雯,张骐,方明星.帕瑞昔布钠用于老年患者前列腺电切术后镇痛及对肾功能的影响[J].安徽医药,2011,15(6):756-757.
作者姓名:崔雯  张骐  方明星
作者单位:安徽省芜湖市第二人民医院麻醉科,安徽,芜湖,241000;安徽省芜湖市第二人民医院麻醉科,安徽,芜湖,241000;安徽省芜湖市第二人民医院麻醉科,安徽,芜湖,241000
摘    要:目的 观察帕瑞昔布钠用于老年患者前列腺电切术后镇痛疗效及对肾功能的影响.方法 80例60岁以上老年患者行前列腺电气化手术,ASAⅠ~Ⅱ级,年龄60~91岁,均采用脊麻-硬膜外联合麻醉.随机分为A、B两组,每组40例,A组术前静脉注射帕瑞昔布钠40 mg(用生理盐水稀释至5 ml),B组术前静脉注射生理盐水5 ml.记录...

关 键 词:帕瑞昔布钠  老年患者  术后镇痛  肾功能

Effect of peri-operative analgesia with Parecoxib on renal function for electrovaporization-ablation of the prostate on elderly patients
CUI Wen,ZHANG Qi,FANG Ming-xing.Effect of peri-operative analgesia with Parecoxib on renal function for electrovaporization-ablation of the prostate on elderly patients[J].Anhui Medical and Pharmaceutical Journal,2011,15(6):756-757.
Authors:CUI Wen  ZHANG Qi  FANG Ming-xing
Institution:CUI Wen,ZHANG Qi,FANG Ming-xing(Anesthesia Department,The Second People's Hospital of Anhui Wuhu,Wuhu 241000,China)
Abstract:Aim To observe the effect of peri-operative analgesia with Parecoxib for electrovaporization-ablation of the prostate on elderly patients.Methods Eighty patients older than 60 who received electrovaporization-ablation of the prostate were randomly divided into A and B groups,ASAⅠ-Ⅱ,age between 60 and 91 years old,anesthetized with combined spinal epidural anesthesia(CSEA).Patients in group A(n=40)received intravenous injection Parecoxib of 40 mg(diluted to 5 ml with normal saline)before surgery while patients in group B(n=40)received normal saline 5 ml.The vital signs at 1,4,8,24 and 48 h after surgery were recorded.The incidence of pain,VAS of pain and the grade 0~3 of pain were observed respectively.Also,creatinine(Cr)and blood urea nitrogen(BUN)were tested before surgery,at the time of 1,4,8,24 and 48 h.Results The vital signs of the patients in two groups were basically stable.The incidence of pain in group A was 12.5%,which were remarkably lower than those in group B which was 75%(P0.01),and the levels of the pain were lower in group A than that in group B.There was no obvious difference in Cr and BuN between the two groups.Conclusion Peri-operative analgesia with Parecoxib for electrovaporization-ablation of the prostate on elderly patients has a perfect analgesics effect,and it has no effects on the renal function.
Keywords:Parecoxib  elderly patients  peri-operative analgesia  renal function  
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