颅脑外伤与继发性癫痫关系的临床观察及药物治疗

目的探讨颅脑外伤与继发性癫痫的关系及药物治疗。方法回顾分析421例颅脑外伤患者中47例继发性癫痫患者的临床资料，研究癫痫与损伤类型、颅脑损伤严重程度、脑电图检查情况及损伤部位的关系。结果开放性脑损伤癫痫发生率（28．21％），明显高于闭合性脑损伤（7．29％）；重伤癫痫发生率（24．11％）明显高于轻伤（3．47％）；顶叶损伤癫痫发生率最高（55．31％）．外伤性癫痫首次脑电图检查异常率为80．85％。经两年抗癫痫治疗，发作完全控制。结论脑外伤后继发性癫痫以开放性损伤、重度损伤发生率高，顶叶损伤最易发生癫痫，以部分性发作居多，脑电图检查在本病的诊断和指导治疗中具有重要意义。对于具有癫痫高危因素的颅脑外伤患者可使用抗癫痫药物预防癫痫发作，积极处理原发伤，合理治疗，可降低发病率，选择恰当的方法治疗癫痫，可提高疗效。

Clinical observation and treatment for secondary epilepsy in patients with traumatic brain injure

Aim To investigate the relations of traumatic brain injury(TBI)and secondary epilepsy in patients after operation and medicine treatment.Method Forty seven cases of TBI with secondary epilepsy patient′s clinicals material had been analyzed fetrosgectively from 421 cases,Relations between epilepsy and damage type,TBI serious nees,electroencephalogram,and the damage spot were studied.Results The open TBI with secondary epilepsy incidence rate(28.21%) obviously was higher than the closed brain injury(7.29%).The severely wounded epilepsy incidence rate(24.11%)was obviousy higher than the minor injury(3.47%).The parietal lobe damage epilepsy formation rate was the highest(55.31%).The traumatic epilepsy electroencephalogram inspection rate of abnormality was 80.85% for the first time.After two years anti-epilepsy,satisfactory results were achieved.Conclusions The formation rate of TBI with secondary epilepsy is higher in the of terating open injury and heavy damage,and the parietal lobe damage is the reault in sequential epilepsy,with a majority of partial seizures.Electroencephalogram has a vital significance in the diagnosis and instruction treatment in this sick.Regarding has epilepsy high-risk factor TBI patient to use the anti-epileptic prevention epileptic paroxysm.Positive and reasonable treatment of primary wound may reduce the disease incidence rate,and the appropriate treatment may enhance the curative effect.