| 太子参多糖对四氧嘧啶糖尿病小鼠的治疗作用 |
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| 引用本文： | 倪受东,夏伦祝,徐先祥,张睿.太子参多糖对四氧嘧啶糖尿病小鼠的治疗作用[J].安徽医药,2010,14(5):521-522. |
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| 作者姓名： | 倪受东 夏伦祝 徐先祥 张睿 |
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| 作者单位： | 安徽省巢湖市第一人民医院药剂科,安徽,巢湖,238000;安徽中医学院第一附属医院药学部,安徽,合肥,230031 |
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| 基金项目： | 安徽省教育厅自然科学研究项目 |
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| 摘 要： | 目的观察太子参多糖对四氧嘧啶糖尿病小鼠的治疗作用。方法选用雄性小鼠,尾静脉注射四氧嘧啶90 mg.kg-1建立小鼠糖尿病模型,太子参多糖按0.375、0.75、1.5 g.kg-1三种剂量给药,测定了糖尿病小鼠体重、空腹血糖、肝糖原含量以及免疫器官脾脏和胸腺的脏体指数。结果太子参多糖可显著降低糖尿病小鼠血糖,增加体重,增加肝糖原含量,增加脾脏和胸腺指数。结论太子参多糖对糖尿病小鼠具有显著的治疗作用。
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| 关 键 词： | 太子参多糖 四氧嘧啶 糖尿病 小鼠 |
Effect of pseudostellaria polysaccharides in diabetic mice by alloxan |
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| NI Shou-dong,XIA Lun-zhu,XU Xian-xiang,ZHANG Rui.Effect of pseudostellaria polysaccharides in diabetic mice by alloxan[J].Anhui Medical and Pharmaceutical Journal,2010,14(5):521-522. |
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| Authors: | NI Shou-dong XIA Lun-zhu XU Xian-xiang ZHANG Rui |
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| Institution: | NI Shou-dong1,XIA Lun-zhu2,XU Xian-xiang2,ZHANG Rui2(1.Department of Phar,The First Hospital of Chaohu City,Chaohu,Anhui 238000; 2.Department of Phar,The First Affiliated Hospital of Anhui TCM College,Hefei 230031) |
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| Abstract: | Aim To study the effects of pseudostellaria polysaccharides in diabetic mice by alloxan.Methods The diabetic mice model was established by alloxan 90 mg·kg-1 iv.Effects of pseudostellaria polysaccharides on diabetic mice were observed at the dosage of 0.375,0.75,1.5 g·kg-1.Results Compared with diabetic model group,pseudostellaria polysaccharides can significantly decrease fasting blood glucose level,increase body weight as well as index of thymus and spleen.Conclusions It was indicated that pseudostellaria polysaccharides has obvious effects on diabetes mellitus. |
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| Keywords: | pseudostellaria polysaccharides alloxan diabetes mellitus mice |
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