| 原发性高血压患者颈动脉内膜中层厚度与hsCRP Hcy及血压变异性相关性研究 |
| |
| 引用本文： | 朱章进,张小玲,张灿,游杨杨,苏浩,严激.原发性高血压患者颈动脉内膜中层厚度与hsCRP Hcy及血压变异性相关性研究[J].安徽医药,2015,36(7):793-796. |
| |
| 作者姓名： | 朱章进 张小玲 张灿 游杨杨 苏浩 严激 |
| |
| 作者单位： | 230022 合肥 安徽医科大学附属省立医院心血管内科,230022 合肥 安徽医科大学附属省立医院心血管内科,230022 合肥 安徽医科大学附属省立医院心血管内科,230022 合肥 安徽医科大学附属省立医院心血管内科,230022 合肥 安徽医科大学附属省立医院心血管内科,230022 合肥 安徽医科大学附属省立医院心血管内科 |
| |
| 基金项目： | 安徽省软科学研究项目(12020503078) |
| |
| 摘 要： | 目的 研究原发性高血压患者血浆中同型半胱氨酸(Hcy)及超敏C反应蛋白(hsCRP)的含量,探讨其与原发性高血压患者颈动脉内膜中层厚度(IMT)和动态血压变异性(BPV)之间的关系。方法 对180例原发性高血压患者行颈动脉彩超测定IMT,按IMT厚度分为,IMT正常组、IMT增厚组、IMT斑块组;并检测24 h动态血压、血Hcy、血清hsCRP。结果 原发性高血压患者颈动脉IMT增厚组、颈动脉IMT斑块组血清hsCRP、Hcy及BPV明显高于颈动脉IMT正常组,差异有统计学意义(均P<0.05)。结论 原发性高血压患者血清Hcy、hsCRP、以及血压变异性与颈动脉粥样硬化之间密切相关
|
| 关 键 词： | 原发性高血压 同型半胱氨酸 超敏C反应蛋白 内膜中层厚度 颈动脉 血压变异性 |
| 收稿时间： | 2015/2/3 0:00:00 |
| 修稿时间： | 2015/4/17 0:00:00 |
Relationship between level and variability of blood pressure(BPV), high-sensitivity C-reactive protein(hsCRP), homocysteine(Hcy) and intima-media thickness(IMT) of carotid artery |
| |
| Zhu Zhangjin,Zhang Xiaolin,Zhang Can.Relationship between level and variability of blood pressure(BPV), high-sensitivity C-reactive protein(hsCRP), homocysteine(Hcy) and intima-media thickness(IMT) of carotid artery[J].Anhui Medical and Pharmaceutical Journal,2015,36(7):793-796. |
| |
| Authors: | Zhu Zhangjin Zhang Xiaolin Zhang Can |
| |
| Institution: | Department of Cardiology, Anhui Provincial Hospital Affiliated to Anhui Medical University, Hefei 230001, China,Department of Cardiology, Anhui Provincial Hospital Affiliated to Anhui Medical University, Hefei 230001, China,Department of Cardiology, Anhui Provincial Hospital Affiliated to Anhui Medical University, Hefei 230001, China,Department of Cardiology, Anhui Provincial Hospital Affiliated to Anhui Medical University, Hefei 230001, China,Department of Cardiology, Anhui Provincial Hospital Affiliated to Anhui Medical University, Hefei 230001, China and Department of Cardiology, Anhui Provincial Hospital Affiliated to Anhui Medical University, Hefei 230001, China |
| |
| Abstract: | Objective To explore the correlation among intima-media thickness(IMT) of carotid artery, high-sensitivity C-reactive protein and the parameter of ambulatory blood pressure monitoring. Methods A total of 180 patients with primary hypertension were divided into three groups according to IMT: the normal group, the thickness group and the plaque group. High-sensitivity C-reactive protein, homocysteine and ambulatory blood pressure were also measured in every patient. Results Variability of blood pressure, high-sensitivity C-reactive protein, homocysteine were higher in plaque group and thickness group than those in normal group(P<0.05). Conclusion IMT is closely related to BPV, hsCRP and Hcy in patients with primary hypertension. |
| |
| Keywords: | Primary hypertension Homocysteine High-sensitivity C-reactive protein Intima-media thickness(IMT) of carotid artery Variability of blood pressure |
|
| 点击此处可从《安徽医药》浏览原始摘要信息 |
| 点击此处可从《安徽医药》下载免费的PDF全文 |
|
