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钙也是双刃剑?
引用本文:王振纲,薛全福.钙也是双刃剑?[J].中国药理学通报,2008,24(11).
作者姓名:王振纲  薛全福
作者单位:1. 中国医学科学院基础医学研究所·北京协和学院基础学院药理学系,北京,100005
2. 中国医学科学院基础医学研究所·北京协和学院基础学院生理和病理生理学系,北京,100005
摘    要:我国居民需安全有效的补钙和阻钙,为了科学应用钙制剂和钙阻断剂,作者提出钙有双向作用,犹如双刃剑,作者从介绍钙代谢基础知识入手,阐述过度补钙和细胞内钙超载的不良作用和可能的危害,以趋利避弊,更好地应用和发挥钙制剂和钙阻断剂的效用。

关 键 词:钙制剂  钙阻断剂  钙代谢  钙超载  补钙和阻钙  双刃剑

Calcium/also a double-edged sword?
WANG Zhen-gang,XUE Quan-fu.Calcium/also a double-edged sword?[J].Chinese Pharmacological Bulletin,2008,24(11).
Authors:WANG Zhen-gang  XUE Quan-fu
Institution:WANG Zhen-gang1,XUE Quan-fu2(1.Dept of Pharmacology,2.Dept of physiology , Pathophysiology,Insitute of Basic Medical Sciences,Chinese Academy of Medical Science,School of Basic Medicine,Paking Union Medical College,Beijing 100005,China)
Abstract:Calcium supplement is needed for Chinese people.Calcium antagonists are also used in China.Authors suggest that calcium owns dual direction effects like a double-edged sword.Based on the knowledge of calcium metabolism,the adverse drugs reactions of excessive calcium supplement and the harmful effects of cellular calcium overload are introduced.Scientific and efficient application of calcium agents and calcium antagonists is expected.
Keywords:calcium agents  antagonists  calcium metabolism  calcium overload  calcium supplement and calcium antagonists application  double-edged sword  
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