| 小剂量A型肉毒毒素治疗面肌痉挛 |
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| 引用本文： | 常建军,梅海云,刘宪平,周秀丽,李浩,王蕾.小剂量A型肉毒毒素治疗面肌痉挛[J].中国新药与临床杂志,2002,21(6):377-377. |
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| 作者姓名： | 常建军 梅海云 刘宪平 周秀丽 李浩 王蕾 |
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| 作者单位： | 信阳市中心医院,神经科,河南,信阳,464000 |
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| 摘 要： | 目的 :探讨小剂量 (2 .0U )A型肉毒毒素局部注射治疗面肌痉挛的临床疗效和安全性。方法 :面肌痉挛病人 5 8例 (男性 2 4例 ,女性 34例 ;年龄 4 7a±s 13a)采用A型肉毒毒素 (2 .0U )局部多点注射痉挛肌肉 ,治疗前后对照。结果 :治疗面肌痉挛 5 8例 ,有效率 97% (5 6 /5 8) ,作用持续 15wk± 4wk。副作用轻微、可逆。结论 :小剂量A型肉毒毒素治疗面肌痉挛疗效肯定 ,副作用少
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| 关 键 词： | 肉毒毒素A型 肌痉挛 面部肌肉 |
| 文章编号： | 1007-7669(2002)06-0377-02 |
Small dosage of botulinum toxin type A in treating hemifacial spasm |
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| Abstract: | AIM: To evaluate the efficacy and safety of small dosage(2.0 U) of botulinum toxin type A(BTA) in treating hemifacial spasm. METHODS: Fifty-eight patients(M 24,F 34; age 47 a±s 13 a) with hemifacial spasm were injected with BTA 2.0 U on the spasmodic muscles. The efficacy and side effects were compared between the results before and after injection. RESULTS: Fifty-eight patients with hemifacial spasm received injection. The effective rates and average relief duration were 97 %(56/58) and 15 wk±4 wk. Side effects were mild and reversible. CONCLUSION: Local injection of small dosage of BTA in treating hemifacial spasm is effective and side effects are less. |
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| Keywords: | botulinum toxin type A muscle spasticity facial muscles |
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