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卡尼汀治疗急性脑梗死
引用本文:林修,叶榕,王耀新. 卡尼汀治疗急性脑梗死[J]. 中国新药与临床杂志, 2001, 20(2): 121-122
作者姓名:林修  叶榕  王耀新
作者单位:福州市第一医院,
摘    要:目的 :观察卡尼汀治疗急性脑梗死的疗效及不良反应。方法 :135例经CT或MRI证实的急性脑梗死病人随机分为 2组。在常规治疗基础上卡尼汀组 68例 (男性 37例 ,女性 31例 ;年龄 60a±s17a) ,用卡尼汀 2~ 3g溶于氯化钠注射液 2 0 0mL ,静脉滴注 ,qd× 2 8d。对照组 67例 (男性 39例 ,女性 2 8例 ;年龄 63a± 17a) ,用右旋糖酐 4 0葡萄糖注射液 50 0mL加复方丹参注射液 2 0mL ,静脉滴注 ,qd× 2 8d。结果 :卡尼汀组总有效率为 80 % ,对照组总有效率为 55% ,P <0 .0 5。治疗期间未发现不良反应。结论 :卡尼汀治疗急性脑梗死是安全、有效的

关 键 词:脑梗死  卡尼汀  丹参  右旋糖酐类
文章编号:1007-7669(2001)02-0121-02

Carnitine in treatment of acute cerebral infarction
Lin Xiu,YE Rong,WANG Yao-Xin. Carnitine in treatment of acute cerebral infarction[J]. Chinese Journal of New Drugs and Clinical Remedies, 2001, 20(2): 121-122
Authors:Lin Xiu  YE Rong  WANG Yao-Xin
Abstract:AIM: To study the efficacy and adverse reactions of carnitine on patients with acute cerebral infarction. METHODS: One hundred and thirty-five patients with acute cerebral infarction diagnosed by CT or MRI were randomly divided into 2 groups, on the basis of conventional therapy. Sixty-eight patients in carnitine group (M37,F31; age 60 a± s 17 a) received carnitine 2-3g, iv, drip, qd for 28 d. The other 67 patients of control group (M39, F28; age 63 a±17 a) received compound salvia miltirrhiza 20 mL in dextran-40 glucose injection 500 mL, iv, drip, qd for 28 d. RESULTS: The total effective rates of carnitine group and control group for acute cerebral infarction were 80% and 55%, respectively (P<0.05). No adverse reactions were found. CONCLUSION: Carnitine is safe and effective in the treatment of acute cerebral infarction.
Keywords:cerebral infarction   carnitine   salvia miltiorrhiza   dextrans
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