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一种草苔虫中的神经酰胺类化合物
引用本文:周光雄,黄美燕,石建功.一种草苔虫中的神经酰胺类化合物[J].中国海洋药物,2005,24(6):37-40.
作者姓名:周光雄  黄美燕  石建功
作者单位:1. 暨南大学药学院,广东,广州,510632
2. 中国医学科学院药物研究所,北京,100050
摘    要:目的研究草苔虫Bugula sp.的化学成分。方法利用Sephadex-LH-20和硅胶拄层析分离化合物,用光谱数据确定化合物结构。结果从产于我国南海深圳大亚湾海域一种草苔虫(Bugula sp.)的CH2Cl2提取物中,分离得到了8个神经酰胺类化合物(1~8)并确定了它们的化学结构。结论神经酰胺类化合物为首次从该海洋物种中得到。

关 键 词:草苔虫  神经酰胺  脑苷脂类
文章编号:1002-3461(2005)06-0037-04
收稿时间:2005-01-17
修稿时间:2005-01-17

Ceramides and cerebrosides from Bugula neritina
ZHOU Guang-xiong,HUANG Mei-yan,SHI Jiang-gong.Ceramides and cerebrosides from Bugula neritina[J].Chinese Journal of Marine Drugs,2005,24(6):37-40.
Authors:ZHOU Guang-xiong  HUANG Mei-yan  SHI Jiang-gong
Institution:1. College of Pharmacy, J inan University, Guangzhou 510300, China; 2. Chinese Academy of Medical Sciences, Institute of Materia Medica , Beijing 100050, China
Abstract:Objective To study the chemical constituents from Bugula sp.Methods Compounds were isolated by organic solvent extraction,sephadex-LH-20column chromatography and silica gel column.Their chemical structures were identified on the basis of spectroscopic data.Results From the CH_(2)Cl_(2)-suluable extract of Bugula sp.,eight ceramides or cerebrosides(1~8) were isolated,and their structures were determined.Conclusion All the compounds were isolated for the first time from Bugula sp..
Keywords:Bugula sp    ceramides  cerebrosides
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