| 利奈唑胺注射剂致血小板减少26例文献分析 |
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| 引用本文： | 刘丛海,彭绍贤,孙小东,冯靖熊.利奈唑胺注射剂致血小板减少26例文献分析[J].中国现代医药杂志,2011,13(4):67-69. |
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| 作者姓名： | 刘丛海 彭绍贤 孙小东 冯靖熊 |
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| 作者单位： | 四川省达州市中心医院,635000 |
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| 摘 要： | 目的探讨利奈唑胺注射液引起血小板减少的一般规律和特点,为临床合理用药提供参考。方法 通过检索《中国医院数字化期刊群》和《维普医学期刊数据库》1979～2010年国内医药学期刊,共收集利奈唑胺注射剂致血小板减少27例,除1例联合可疑致血小板降低抗菌药头孢哌酮舒巴坦外,其他26例均可排除其它可疑药物,采用文献计量学方法对病历的资料进行整理与归纳。结果男21例(76.92%),女6例(23.08%%);其中年龄最大96岁,最小1岁;给药剂量除1岁患者150mg外,其余均为600mg静脉滴注;不良反应多发生在用药7～14天(60.00%),停药后恢复时间3～25天。结论掌握利奈唑胺致血小板减少的特点将有助于该药的安全使用。
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| 关 键 词： | 利奈唑胺 血小板减少 不良反应 |
Literature analysis of 26 cases of Linezolid injection-induced thrombocytopenia |
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| Liu Conghai,Peng Shaoxian,Sun Xiaodong,et al..Literature analysis of 26 cases of Linezolid injection-induced thrombocytopenia[J].Modern Medicine Journal of China,2011,13(4):67-69. |
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| Authors: | Liu Conghai Peng Shaoxian Sun Xiaodong |
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| Institution: | Liu Conghai,Peng Shaoxian,Sun Xiaodong,et al. Dazhou Central Hospital,Sichuan 635000 |
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| Abstract: | Objective To study linezolid injection induced thrombocytopenia and characteristics of the general rule, provide a reference for the clinical use of drugs. Methods By searching the China Hospital Digital Periodicals and VIP medical journal database 1979~2010 the domestic medical journals, collected linezolid injection induced thrombocytopenia in 27 cases, suspicious in 1 case combined cephalosporin antibiotic induced thrombocytopenia piperazine ketone sulbactam, the other 26 cases were available for the exc... |
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| Keywords: | Linezolid Thrombocytopenia Adverse reactions |
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