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国产与进口低分子量肝素钠注射液治疗不稳定性心绞痛的比较
引用本文:何书英,吴汇荣,张婉文,张晖,陆风翔,黄元铸.国产与进口低分子量肝素钠注射液治疗不稳定性心绞痛的比较[J].中国生化药物杂志,2000,21(2):88-89.
作者姓名:何书英  吴汇荣  张婉文  张晖  陆风翔  黄元铸
作者单位:1. 210093,南京南大药业有限责任公司
2. 江苏省人民医院
摘    要:目的:比较国产与进口低分子量肝素钠注射液(LMWH)在治疗不稳定性心绞痛方面的临床疗效。方法:治疗组与对照组各30例,腹壁皮下脂肪内注射,剂量为100抗XaIU/(kg·12h),连续7d。结果:国产LMWH治疗不稳定性心绞痛显效率及有效率分别为33.3%和83.3%,与进口低分子量肝素钠注射液(法安明)的30.0%和80.0%无显著差异。结论:国产LMWH对不稳定性心绞痛的治疗安全有效,且与进口同类产品相一致。

关 键 词:低分子量肝素钠  法安明  不稳定性心绞痛
修稿时间:1999-03-15

Comparison between China-made and Exported Low Molecular Weight Heparin Sodium in Treating Unstable Angina Pectories
He Shuying,Wu Huirong,Zhang Wanwen,Zhang Hui,Lu Fengxiang,Huang Yuanzhu.Comparison between China-made and Exported Low Molecular Weight Heparin Sodium in Treating Unstable Angina Pectories[J].Chinese Journal of Biochemical Pharmaceutics,2000,21(2):88-89.
Authors:He Shuying  Wu Huirong  Zhang Wanwen  Zhang Hui  Lu Fengxiang  Huang Yuanzhu
Institution:He Shuying ,Wu Huirong ,Zhang Wanwen ,Zhang Hui ,Lu Fengxiang ,Huang Yuanzhu (Nangjing University Pharmaceutical Factory Nanjing 210093)
Abstract:Purpose: To compare the therapeutic effects of China-made LMWH and exported LMWH(Fragmin). Methods: Treatment group and control group both have 30 patients and two subcutaneous injection daily for 7 days (100 antiXaIU/(kg ·12h ). Results: The remarkable improving rate and improving rate of China-made LMWH are 33. 3 % and 83. 3 % respectively and there is no notable difference with exported Fragmin (30. 0% and 80. 0% ). Conclusion: It is proved that China-made LMWH in tratment of unstable angina pectories is both effective and safe.
Keywords:Low molecular weight heparin  Fragmin  Unstable angina pectories
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