| 玻璃酸钠对关节腔内注入木瓜蛋白酶所致兔膝关节退行性改变的改善作用 |
| |
| 引用本文： | 凌沛学,苏淮,贺艳丽,白若琬,王韶进,张天民.玻璃酸钠对关节腔内注入木瓜蛋白酶所致兔膝关节退行性改变的改善作用[J].中国生化药物杂志,1996(6). |
| |
| 作者姓名： | 凌沛学 苏淮 贺艳丽 白若琬 王韶进 张天民 |
| |
| 作者单位： | 山东正大福瑞达制药有限公司!济南250014(凌沛学，苏淮，贺艳丽，白若琬)，山东医科大学附属医院(王韶进)，山东医科大学药学系(张天民) |
| |
| 摘 要： | 采用在兔膝关节内注入木瓜蛋白酶造成的膝关节退行性改变模型,考察关节腔内长期多次注射玻璃酸钠对这种退行性改变的抑制和改善作用。结果表明:玻璃酸钠对已造成退行性改变的关节软骨有减轻和改善其病变程度的作用。
|
| 关 键 词： | 玻璃酸钠 木瓜蛋白酶 退行性改变 |
Effects of Sodium Hyaluronate on Experimental Knee Joint Degeneration Induced by Intra-articularly Applied Papain in Rabbits |
| |
| Ling Peixue,Su Huai,He Yanli,Wang Shaojin,Bai Ruowan,Zhang Tianmin Shandong C. P Freda Pharm Co. Ltd..Effects of Sodium Hyaluronate on Experimental Knee Joint Degeneration Induced by Intra-articularly Applied Papain in Rabbits[J].Chinese Journal of Biochemical Pharmaceutics,1996(6). |
| |
| Authors: | Ling Peixue Su Huai He Yanli Wang Shaojin Bai Ruowan Zhang Tianmin Shandong C P Freda Pharm Co Ltd |
| |
| Institution: | Jinan 250014 |
| |
| Abstract: | A rabbit's knee joint usJeoarthritis model was obtained by papain injection into the articular. The effects of sodium hyaluronate (SH) on restraining the joint degenerative changes and recovering from the change was investigated by long-term injections intra-articularly on many occasions. The results suggested that SH had improving effects to the damaged cartilage which insulted by papain treatment and be beneficial to the recoverv of osteoarthritis. |
| |
| Keywords: | Sodium hyaluronate Papain Degeneration |
| 本文献已被 CNKI 等数据库收录！ |
