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Calcium Enabled Remote Loading of a Weak Acid Into pH-sensitive Liposomes and Augmented Cytosolic Delivery to Cancer Cells via the Proton Sponge Effect |
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| Authors: | Yang Mimi M Yarragudi Sasi Bhushan Jamieson Stephen M F Tang Mingtan Wilson William R Wu Zimei |
| Institution: | 1.School of Pharmacy, The University of Auckland, Auckland, 1142, New Zealand ;2.Auckland Cancer Society Research Centre, The University of Auckland, Auckland, New Zealand ; |
| Abstract: | Pharmaceutical Research - While delivery of chemotherapeutics to cancer cells by nanomedicines can improve therapeutic outcomes, many fail due to the low drug loading (DL), poor cellular uptake and... |
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