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低分子肝素钙与依达拉奉联合治疗对进展性脑梗死的疗效及血清一氧化氮的影响
引用本文:叶冠龙.低分子肝素钙与依达拉奉联合治疗对进展性脑梗死的疗效及血清一氧化氮的影响[J].中国医院用药评价与分析,2010(4):335-336.
作者姓名:叶冠龙
作者单位:上海市徐汇区大华医院;
摘    要:目的:观察低分子肝素钙与依达拉奉联合治疗进展性脑梗死的疗效及血清一氧化氮(NO)的影响。方法:将我院收治的120例发病72h内的进展性脑梗死患者随机分为3组。对照组:疏血通+胞二磷胆碱,连用14d;抗凝组:低分子肝素钙,连用7d;治疗组:依达拉奉(连用14d)+低分子肝素钙(连用7d)。观察治疗后28d的临床疗效及神经功能缺损程度,同时检测血清一氧化氮(NO)含量。结果:治疗组疗效优于抗凝组(P〈0.05),抗凝组疗效优于对照组(P〈0.05);与对照组和抗凝组相比,治疗组NO含量降低。结论:低分子肝素钙联合依达拉奉对治疗进展性脑梗死疗效显著,与抑制NO的异常表达有关。

关 键 词:低分子肝素钙  依达拉奉  脑梗死

Efficacy of Low Molecular Weight Heparin Calcium Combined Edaravone for Progressive Cerebral Infarction and Its Effects on Serum Nitric Oxide
YE Guan-long.Efficacy of Low Molecular Weight Heparin Calcium Combined Edaravone for Progressive Cerebral Infarction and Its Effects on Serum Nitric Oxide[J].Evaluation and Analysis of Drug-Use in Hospital of China,2010(4):335-336.
Authors:YE Guan-long
Institution:YE Guan-long(Shanghai Xuhui District Dahua Hospital,Shanghai 200030,China)
Abstract:OBJECTIVE:To observe the efficacy of low molecular weight heparin calcium combined edaravone for progressive cerebral infarction and its effects on serum nitric oxide.METHODS:120 patients admitted to our hospital on account of onset of progressive cerebral infarction within 72h were randomly divided into 3 groups:control group received Shuxuetong plus cytidine diphosphate choline for 14 days;anticoagulative group received low molecular weight heparin calcium for 7 days,and trial group received edaravone for...
Keywords:Low molecular weight heparin calcium  Edaravone  Cerebral infarction  
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