101例药品不良反应报告分析

目的：了解我院药品不良反应（ADR）发生情况及ADR报告填写质量，促进临床合理用药。方法：对我院2006年收集的101例ADR报告分别从患者性别、年龄、给药途径、涉及药物种类以及ADR临床具体表现等方面进行统计、分析。结果：由抗茵药物导致的ADR最多，占总数的46．5％（47例）。101例ADR中60岁以上老年患者较多，占总例数的35．6％（36例），20岁以下的患者较少，占总数的4％（4例）；以静脉滴注方式92．1％（93例）为主；临床表现以皮肤及附件损伤最常见，占总例数的39．6％（40例）。结论：临床应重视ADR报告和监测工作，合理使用抗茵药物，避免或减少ADR发生。

Analysison Monitoring Reports of 101 Cases of Adverse Drug Reactions in Our Hospital

OBJECTIVE： To review the occurrence of adverse drug reaction （ADR） in our hospital and to promotoe a rational clinical drug use. METHODS： 101 ADR reports collected in our hospital in 2006 were analyzed statistically in terms of patients＇ age distribution, route of administration, drug varieties and the specific clinical manifestations. RESULTS： Antibiotic was the first major factor causing ADR it accounted for 46.5% （47cases）. Among the 10! cases, most were senile patients, whom accounted for 35.6% （36cases）. Most ADR were induced by ivgtt, which accounted for 92.1% （93cases）. The most common clinical manifestations were the damage of skin and adnexa. The following was the Circulatory system and Digestive system adverse reaction. CONCLUSION： Importance should be attached to the reporting and monitor of ADR, the use of antibacterials should be rationalized to lessen AND avoid the occurrence of ADR.