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抗骨质疏松药物不良反应回顾性分析
引用本文:汤静,潘慧,徐松,刘皋林.抗骨质疏松药物不良反应回顾性分析[J].中国医院用药评价与分析,2008,8(12):950-951.
作者姓名:汤静  潘慧  徐松  刘皋林
作者单位:[1]上海交通大学附属第一人民医院临床药学室,上海市200080 [2]南京医科大学药学院,南京市210029
摘    要:目的:分析抗骨质疏松药物引起不良反应的原因。方法:检索国内外期刊2000~2008年有关抗骨质疏松药物所致不良反应的个案报道及综述。结果:抗骨质疏松药物的不良反应发生率不高,程度较轻,常见于胃肠道不适。结论:可通过合理配伍,联合用药来减少不良反应发生率;如长期用药,其安全性需密切关注。

关 键 词:抗骨质疏松药物  不良反应  回顾性分析

Retrospective Analysis on the Adverse Drug Reactions Induced by Anti-osteoporotic Drugs
Institution:TANG Jing, PAN Hui, XU Song, LIU Gao-lin (1. Dept. of Clinical Pharmacy, Shanghai Jiaotong University Affiliated First people ' s Hospital, Shanghai 200080, China ; 7. Dept. of Pharmacy, Nanjing Medicial College, Nanjing 210029, China)
Abstract:OBJECTIVE:To analyze the causes of adverse drug reactions (ADRs) induced by anti-osteoporosis drugs. METHODS: Individual case reports and review articles about the anti-osteoporosis drug-induced ADR reported in journals both at home and abroad during the period 2000 - 2008 were retrieved. RESULTS:The incidence of anti-osteoporosis druginduced ADRs was low and the degree was light, which manifested chiefly as discomfort of gastrointestinal tract. CONCLUSION:The reduction of the incidence of anti-osteoporosis drug-induced ADRs relies on rational combination and combined drug use. Great attention should be attached to the safety of anti-osteoporosis drugs if used for a long term.
Keywords:Anti-osteoporotic drugs  Adverse drug reaction  Retrospective analysis
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